6344 resultaten
We hypothesize that TIPS placement has an significant effect on drug metabolism and bile acid metabolism.
Primaire doelstelling:Het doel van deze studie is om het aantal kinderen te onderzoeken dat een fietshelm gebruikt na een bezoek aan de spoedeisende hulp (SEH) na een fietsongeluk, vergeleken met kinderen die dat niet hebben gehad.Secundaire…
The aim of this study is twofold: 1)To assess the effectiveness of a CPG converted into a CDSS, in actually preventing the development of WSLs during orthodontic treatment with fixed appliances compared to usual preventive measures. 2)To evaluate…
To evaluate the cost-effectiveness of therapies for male subfertility.
Part A The main objective of this part of the study is to develop a pharmacokinetic model for [18F]PSMA. Furthermore, use of simplified quantitative methods and procedures will be performed and validated against full quantitative kinetic measures,…
That intermuscular dissection of polyps suspected of deep submucosal invasive carcinoma can result in the radical (R0) excision of > 85% of the carcinomas, and that the risk of local recurrence is below 4%.
With this study we want to test two new modules of a chair specialised for elderly and test whether these new modules improve skin vitality and doe not disturb the users comfort. The new modules apply automatic changes in seating posture after a…
We hypothesize that 20 min of one-legged CWI at 8 degrees Celsius (°C) will lower macro-, microvascular blood flow, and amino acid incorporation in muscle tissue following a bout of resistance-type exercise training when compared with the…
To improve detection of metastases, radiotracers have been developed for PET/CT imaging: i.e. radiolabelled Prostate Specific Membrane Antigen (PSMA) ligands. Initial studies with Gallium-68 (68Ga-) PSMA showed promising results. The second…
Atherosclerosis is characterized by a persistent inflammation of the arterial wall. Monocyte-derived macrophages are the most abundant immune cells in atherosclerotic plaques. It has recently been shown that not only immune cells of the adaptive…
In this pilot study we want to look at different aspects of radiation damage, including effects on microvasculature, blood-brain barrier function and white matter changes. We hypothesize that combining these different imaging modalities (MRI and PET…
Children in the game-based intervention condition will improve more on reading fluency than those in the standard intervention (TUA) condition.
personality traitsinfluence the assessment of echocardiography images with respect to evaluation of LV EF and image quality.
To investigate whether amino acid area under the curve (AUC) and Cmax of product B is equivalent to amino acid AUC and Cmax of product A
We expect that the disproportionally strong clinical effects of fingolimod in relapsing remitting multiple sclerosis can be explained by enhanced functional adaptation mechanisms of the brain and that enhanced functional adaptation will be sustained…
ICPT is more effective in (1) improving patients’ quality of life and social networks, (2) preventing or decreasing professionals’ perception of patients as ‘difficult’, (3) discharging patients to a lower level of care, (4) being less costly in…
To investigate the uptake and effectiveness of a Dementia Risk Reduction Online lifestyle Program among middle-aged descendants of people with recently diagnosed AD or VD at participating Dutch memory clinics.
Comparison of the accuracy of achieved correction of the mechanical axis in the frontal plane relative to preoperative planning endeavouring to achieve 3-4° of valgus between open and closed HTO’s.
Our hypothesis is that older workers in the intervention group will improve lifestyle and thereby vitality at the short term (6 months) and at the long term (12 months), whereas in the control group lifestyle and vitality will remain the same as at…