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Single tooth implants in the aesthetic zone: a prospective study on the clinical performance of Straumann Bone Level Tapere Implants

treatment with the Straumann Bone Level Tapered implant are a reliable option for single tooth replacements in the maxillary aesthetic zone. No significant differences between patients with a preserved alveolar ridge or patients with a non-preserved…

Afbouw strategieën bij door anti-TNF&MTX geïnduceerde remissie bij Reumatoïde Arthritis. Moeten we MTX of anti-TNF als eerste afbouwen?

In RA patients that achieved disease remission by treatment with the combination of a csDMARD and anti-TNF, there is a difference in (cost-)effectiveness when medication is tapered according to strategy A (csDMARD first) compared to strategy B (anti…

Atomoxetine in children with pervasive developmental disorders.

Atomoxetine will be effective in reducing symptoms of inattention and overactivity in children and adolescents with ASD.

Effectiveness of Diclofenac versus Paracetamol in primary care patients with knee osteoarthritis.

What is the effectiveness of Diclofenac compared to Paracetamol over a period of two weeks and if necessarily another two weeks (consistent with the Dutch guidelines for general practitioners) in new consulters with knee osteoarthritis in the…

Effentiveness of Assertive Community Treatment versus Care-as-usual for patients with severe and persistent psychiatric disorders.

ACT will, compared to care-as-usual result in less admission days and more sustained contact with mental health. Moreover, life skills will be more improved possibly resulting in a higher quality of life.

A comparison of the efficacy of oral fumarate and methotrexate therapy in the treatment of severe psoriasis.

N/A

eNose in Head and Neck Cancer.

we hypothesize that an electronic nose can discriminate the VOC pattern in exhaled breath between patients with Head and Neck Cancer from healthy controls.

PILOT STUDY 2: Prevention Of Malnutrition In Senior Subjects (PROMISS)

Participants from both the intervention groups will increase their protein intake more than participants in the control group.

One-stop-shop Study for Treatment of Basal Cell Carcinoma Using Reflectance Confocal
Microscopy

One-stop-shop concept, using real-time in vivo reflectance confocal microscopy as diagnostic tool is non-inferior to standard of care in the surgical management of new primary basal cell carcinoma

Reproducibility and diagnostic accuracy of an internationally-endorsed screening framework for cervical vascular risks following manual therapy and exercise. The Go4Safe trial

We hypothesize that evaluation of the IFOMPT framework gives insight into the reproducibility and diagnostic accuracy of this screening tool for risk estimation of vascular complications among manual-physiotherapists

EPA Incorporation and Immune responses after nutritional supplementation in Cancer patients receiving RadioTherapy.

It is expected that 8 days of supplementation with the study product will contribute to an improved immune response and to increased incorporation of EPA and DHA in white and red blood cells and plasma.

Rotation of antihypertensive drugs in ethnic groups.

Interindividual variation in antihypertensive drug response can be predicted through lifestyle, demographics and plasma drug levels.

Pioglitazone Influence of triglyceride Accumulation in the Myocardium in Diabetes.

Lipotoxicity-related cardiac abnormalities can be reversed by PPAR g agonist therapy in type 2 diabetes patients.

Effects of Cimetidine on Cisplatin-induced Nephrotoxicity.

The nephrotoxicity caused by cisplatin is of great concern both in that it is dose-limiting and can be detrimental to the patient. Much work has been done to reduce or prevent this damage to renal cells, however to date the best approach has reduced…

Evaluation of an educational program on the prevention of complicated infections in patients with diabetes.

A health education program for both patients and general practitioners will change behaviour by 15%.

Dynamic MRI with mapping of T1-values as indicators of disease activity in luminal Crohn’s disease.

To test the accuracy of dynamic MRI with T1 mapping in patients with CD and compare this with know parameters such as CDEIS, CRP and CDAI.

Efficacy of addition of hrHPV testing by Hybrid Capture II to conventional cytological screening for cervical cancer: 5 years follow-up.

In the original study (NTR215), we assessed the 3-year risk of CIN3+ in women stratified for hrHPV and cytology at baseline. In this study, we will assess the 5-year risks. Stratification at baseline is done on hrHPV, cytology, and hrHPV genotype.…

Implementation of the AWR by the ED triage nurse

With implementation of the AWR and APWR by the ED triage nurse we expect a reduction in the total number of radiographs requested, without missing any clinical relevant fractures. We also expect a reduction in overall waiting times at the ED and…

SAFE: Een eHealth interventie voor vrouwen die slachtoffer zijn van partnergeweld

Victims of IPV, living in an unsafe and unhealthy situation, are faced with a broad range of physical and emotional symptoms. Standard and easy-accessible care to facilitate change into a safer situation is lacking. The project aims to launch an…