16235 resultaten
To reduce treatment-related toxicity in patients with localized prostate cancer, focal treatment is warranted. This can be achieved with MRI guided high-dose-rate brachytherapy. We expect that a single dose of 19 Gy to the tumour volume will be of…
Not applicable
Budesonide does not alter the exposure of cabazitaxel in castrate resistant prostate cancer patients.
Hearing aid fitting will reduce the tinnitus burden in patients with mild hearing loss.
1. Is a multidisciplinary cognitive behavioural lifestyle program more effective in losing weight and permanent weight loss for women with PCOS and obesity then regular care? 2. Is a multidisciplinary cognitive behavioural lifestyle program in…
Several reports have indicated that the chemokine receptor CCR5 and its ligands, escpecially CCL5 (formerly known as RANTES), may play a role in the pathogenesis of psoriasis. CCR5 targeted treatment could therefore be a therapeutic option for…
THypothesis: The integration of measurement outcomes in response to the PhenFlex challenge test will enlarge small, single differences by combining multiple but small effects on metabolism leading eventually to a measurable health difference before…
patients with diabetic cardiovascular autonomic neuropathy are more prone to hypotension during surgery and therefore require more inotropic/vaspressor medication perioperatively
Patients who receive treatment as usual (TAU) plus mentalization-based treatment for psychosis (MBT-P) will show a greater improvement in social functioning than patients who receive TAU only. This effect is mediated by an increase of social…
No predetermined hypothesis
Decontamination of the implant surface with 35% phosphoric acid during the surgical treatment of peri-implantitis does result in better clinical and microbiological outcome compared to sterile saline
To demonstrate wether there is difference in tissue oxygen tension and extravascular lung water while patients are being resuscitated with cristalloids or colloids combined with cristalloids.
Consumption of slowly digestible starch is implicated with a decreased risk for the development of obesity, insulin resistance and Type 2 diabetes (T2DM). Underlying mechanisms of this beneficial effect are not yet elucidated. The objective of this…
Baseline variables such as Harm Avoidance and other personality, biological and electrophysiological measures will predict treatment outocme to an SSRI.
6-TG will be a beneficial therapy in about two-thirds of IBD patients whom failed previous therapies, consistent with the literature.
We hypothesize that prevenar 13 elicits a humoral immune response against oxidized low density lipoprotein
Adding a Combined Psychological Intervention to a very low calorie diet is more effective then a very low calorie diet followed by usual care in maintaining weight loss and improving glycaemic control, cardiovascular risk score, psychological…
An homebased medication review intervention conducted by a community pharmacists in close collaboration with the GP and patient improves the quality of pharmacotherapy in elderly patients.
The aims of the study are: 1) To investigate the effectiveness in diminishing behavior problems of Behavioral Parent Training Groningen (BPTG) for parents of children with an ASD and behavioral problems between 4 and 13 years of age in two formats…
1. Orthokin relieves symptoms of pain and dysfunction of OA as determined by the outcome of designated subjective scoring systems; 2. Orthokin reduces inflammatory markers in synovial fluid; 3. Orthokin inhibits long-term radiological progression of…