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Effect of a new synbiotic mixture of short chain galacto-oligosaccharides, long chain fructo-oligosaccharides and Bifidobacterium strain on the gut microbiota of caesarean delivered infants.

The study will investigate the effect of a synbiotic test product compared to a control product on the composition and metabolic activity of the gut microbiota of C-section delivered infants.

B-Positive: Enhancing well-being in patients with bipolar disorder

The primary hypothesis of the study is that a well-being intervention (‘This is your life’) offered to bipolar disorder (BD) patients in remission in addition to usual care (CAU) is more (cost-)effective than CAU only.

Multicenter trial of elective revascularization in patients with diabetes mellitus and mild anginal complaints.

To determine whether a strategy of invasive treatment (relative to continued medical treatment) of patients with type 2 diabetes mellitus, mild symptoms of stable angina pectoris, and documented myocardial ischemia lead to a decrease in cardiac…

Drinking Less, Self help for Problem Drinking: randomised clinical trial.

To test the effectiveness of a self help booklet without therapist guidance vis-à-vis a psycho-education brochure for adult problem drinkers in the general population.

The validity and effectivity of the new checklist ‘Attune & Stimulate’ for parents and caregivers of persons with severe intellectual disabilities (SID).

1) The checklist 'Attune & Stimulate' is a valid instrument to assess the arousal level of clients with SID. 2) Caregivers who are randomized to the intervention group that is instructed to use the A&S-checklist attune…

Two-sample FIT-screening: a 4th screening round

Patient education and postoperative pain.

An educational film seen before surgery change the postoperative expressed need for opioids by the patient (i.e., increase when postoperative patients report NRS > 4 and decrease when patients report NRS ≤ 4).

Asthma, a disease due to a lack of bacterial infections in childhood.

The degree of TH1-skewing by mycobacteria is controlled by NRAMP1 gene polymorphisms and related to the degree of inhibition of TH2-mediated disease.

Alfentanil in CT-colonography.

We hypothesize that alfentanil will reduce maximum pain score by at least 1.3 point on a 11-point numeric rating scale.

Doelbewust diabetes.

It is expected that the intervention will increase participants' proactive coping skills, which will in turn lead to improved self-care behavior and medical outcomes.

The management of actinic keratosis in transplant recipients.

N/A

Study of the efficacy of topically applied cyclosporinsolution on psoriatic nails.

N/A

Phase II trial of combination therapy with oxaliplatin and capecitabine in patients with advanced esophageal cancer.

For patients with metastatic or local-regional unresectable esophageal carcinoma there is no alternative treatment. In this trial it is studied whether combination chemotherapy with oxaliplatin and capecitabine prolongs survival and improves quality…

Posture or Patching (PoP).
Accelerated clearing of the media with massive vitreous hemorrhage and suspected retinal tear.

Binocular patching in combination with posture adherence is superior to posture adherence alone in achieving visualization of the superior fundus quadrants following a vitreous hemorrhage.

SC.20 / CKTO 2004-06
A phase III international randomised trial of singel versus multiple fractions for re-irradiation of painful bone metastases.

To study the effectivity of different retreatment radiotherapy schedules for painful bone metastases.

FLUID MANAGEMENT TARGETED ON DIFFERENT VARIABLES OF PERIPHERAL PERFUSION IN PATIENTS ADMITTED TO THE INTENSIVE CARE UNIT.

We hypothesize that peripheral perfusion targeted fluid management (PPTFM) might prevent excessive fluid administration, leading to less formation of tissue edema, less respiratory dysfunction and shorter duration of mechanical ventilation.

Physical trauma patients with symptoms of an acute and post-traumatic stress disorder: an observational study

The aim is to examine the natural course of Acute Stress Disorder (ASD) symptoms (aim 1) and the effects of these symptoms on the development of Port-Traumatic Stress Disorder (PTSD) and patients¡¯ psychological distress (i.e., anxiety and…

Physical activity and cognitive control in multiproblem young adults

It is hypothesized that physical activity will have a positive (dose-response) effect on cognitive control, measured as error processing, response inhibition and interference effect.

The effect of cold acclimation on brown adipose tissue.

Chronic cold exposure will increase: 1. Basal metabolism and facultative thermogenesis; 2. Brown adipose tissue activity and volume; 3. Skeletal muscle mitochondrial uncoupling and result in BRITE cell recruitment.

The effect of L-arabinose on glycaemic and insulinemic response in a liquid and a solid product.

Consumption of foods containing L-arabinose will improve glycaemic and insulinemic response.