16235 resultaten
Ocular surface inflammation plays a pivotal role in dry eye. The hypothesis of this study is that markers of inflammation expressed by conjunctival epithelial cells can be used to study inflammation and that the topical use of an anti-inflammatory…
Muscle hypoxia, either chronic or intermittent (exercise-induced), is responsible for the altered muscle oxidative phenotype in chronic obstructive pulmonary disease and chronic heart failure through modulation of the regulatory molecules PGC-1/…
The purpose of the study is to evaluate the outcomes and midterm follow-up in the mini-gastric bypass in terms of weight loss, resolution of co-morbidities and the impact of different BP-limb lengths.
Gonadotropins after 5-7 ovulatory cycles with CC will lead to more multiple gestations and higher costs compared with extended CC treatment. Combination of CC or gonadotropins with IUI may result in a higher pregnancy rate.
The present study aims to get more insight into the various aspects that govern adherence to the oral anticancer drug erlotinib in daily practice.
Vitamin D supplementation will improve glycemic control in patients with type 2 diabetes melliuts.
We hypothesize that the percentage of successful TOL will increase with the use of EHG because EHG provides more accurate assessment of UA, allowing for better optimization of the contraction pattern during labor. Besides, more reliable monitoring…
By using a surgical safety checklist, the incidence of postoperative complications will decrease.
The Victoria modules are thought to have a positive effect on acknowlegdement for adversities and risk awareness. This can be used to take acceptable risks in rehabilitation process. This will then lead to more societal participation and less…
1. Regular physical follow-up can partly be replaced by nurse-led telephone follow-up, with at least similar quality of life (QoL), in breast cancer patients treated with curative intent. ( change in QoL < 5 points) 2. An informative/…
A postoperative retransfusion system is most effective in terms of allogeneic blood transfusion rates when in situ for maximum of 6 hours after major orthopaedic surgery.
Administration of Ibopamine hydrochloride eye drops restores intraocular pressure in patients with hypotony following vitreoretinal surgery or uveitis.
The implementation rate of the decision aid in daily care is expected to depend on barriers perceived by care providers and/or patients. Use of the decision aid is expecetd to decrease decisional conflict and increase knowledge in patients.
Urokinase rinsed will lead to less CONS infections in patients with hematological malignancies and central vein catheters.
Care providers are more likely to adhere to clinical practice guidelines when they receive guideline-based decision support by an electronic system.
In this study, we expect to decrease the number of referrals and repeat smears by immediately referring those women who are positive for hrHPV with mildly abnormal smears for colposcopically-directed biopsies. Thus, for the remaining women with BMD…
An upfront RBCT aiming at low-normal Hb levels will ameliorate anemia-caused tumor hypoxia-related resistance to chemotherapy before the start of chemotherapy and may decrease secondary anemia-induced endogenous release of cytokines like VEGF,…
In general practices, proactive care for potentially frail older people with the use of Utrecht Periodic Risk Identification and Monitoring (UPRIM) and the use of a Geriatric Nurse Primary Care (GNPC) will result in better daily functioning in…
Previous randomised trials have shown the efficacy of etanercept in RA patients. In this study we will evaluate the respons of etanercept in anti-TNF naive patients compared to patients who have failed other anti-TNF. We will look for clinical…