16235 resultaten
Pre- and probiotics are able to change the composition of the altered intestinal microbiota that is found in allergic patients, indicating beneficial effects of these nutritional components in the prevention and treatment of allergic diseases. The…
We hypothesise that the Taperloc BoneMaster coated stem is equal or better than conventional porous coated or cemented stem focussing on implant ingrowth and bone remodelling.
1. The increased awareness will lead to numerous small and immediate adaptations of the auditory environment (micro-interventions) and longer-term interventions (macro-interventions). 2. The interventions will improve the quality of the auditory…
It is hypothesized that exercise therapy and CBT are both effective in reducing fatigue and improving activities and QoL in patients with Postpoliomyelitis Syndrome (PPS) compared to the usual care.
By tackling the underlying determinants, we might slow down of prevent undernutrition in community dwelling older adults.
The exerted pressure on the skin by non-invasive pelvic circumferential compression devices (PCCDs) carries a risk of pressure sores and skin necrosis in case of prolonged use. A persons Body Mass Index (BMI) is of influence on this risk.
In the present study we will investigate the efficacy of Lybridos in one group of subjects with FSD in the laboratory. We will measure subjective, physiological and neuropsychological measures of sexual functioning in the Emotional Brain laboratory…
The hypothesis of this study is that omega 3 fatty acid in an artificial tear ameliorates symptoms and ocular surface signs in patients with dry eye.
Uveal melanoma is an uncommon malignancy (0.6-0.7 cases/100.000/year) that, in the case of metastatic stage, has a poor prognosis for response to treatment and survival. It is remarkable for its purely hematogenous pattern of dissemination, most…
The computer-tailored health information in combination with personal counselling leads to: 1. Improvement of health behaviors; 2. Improvement of parental satisfaction with well-child care visits; 3. Improvement of well-child care provider…
COPD management using the COPD Impact Scale and an treatment algoritm, will be more effective in improving the health related quality of life of COPD patients, meausured by the Saint George Respiratory Questionnaire, than usual care, over a period…
Anxiety and depression are highly prevalent in adolescents. Therefore, early and low threshold prevention is of great importance. The aim of the current study is to test whether online training of a positive information processing style and…
We hypothesize that age-related changes in hepatic and intestinal drug metabolism affect the pharmacokinetics of midazolam.
Submacular administration of rtPA for submacular haemorrhages is safe and effective.
1. a. Does influenza vaccination in SLE and Wegener patients result in a decreased humoral immune response compared to healthy age-matched controls?; b. Does influenza vaccination in SLE and Wegener patients result in a decreased cellular immune…
The objective of this study is to support consumers in their decision whether they want to perform a self-test or not. By providing objective information on self-testing, we expect knowledge levels of participants who have viewed the decision aid to…
The main outcome is the identification of clinical, biochemical, and genetic factors associated with resilience to cognitive decline in extreme elderly subjects. At baseline we will test the association between cognitive resilience and amyloid…
1. Modafinil influences fatigue, cognitive functioning, and quality of life of LGG patients; 2. There is a correlation between (changes in) fatigue, cognition, and quality of life on the one hand, and functional connectivity in the brains of LGG…
20 to 30% improvement of scalp cooling results due to longer post-infusion cooling times.