400 resultaten
Combining FOLFIRINOX chemotherapy and stereotactic radiotherapy can lead to better regional tumor control and better overall survival in patients with locally advanced pancreatic cancer.
Percutaneous, ORIF and conservative treated of displaced intra-articular calcaneal fractures have a similar outcome as measured with the AOFAS (American Orthopaedic Foot and Ankle Society) score.
a higher protein intake at the end of the first treatment cycle in patients with CRC or NSCLC undergoing first line treatment with chemo-, concurrent chemoradio- or immunotherapy who are receiving two servings of test product daily and who completed…
Primary objective: To determine the safety of once daily inhalation of the recommended daily dose of tobramycin with the Akita® and the PARI-LC® Plus nebulizer in patients with CF. Systemic absorption can be used as surrogate parameter for safety.…
The prevalence of disinhibited behavior is high in institutionalized people with the behavioral variant of frontotemporal dementia. Disinhibited behavior is associated with reduced well-being of residents and is experienced as an important challenge…
The primary objective of the study is to examine whether the WhiteTeeth app used by orthodontic patients aged 12 to 16 improves oral health behavior and oral hygiene. Primary outcomes of this RCT are dental plaque levels, gingival bleeding upon…
As EGFR plays a role in pathogenesis of both pulmonary arterial hypertension and systemic sclerosis, EGFR inhibition will lead to beneficial effects in disease course.
We hypothesize that clarifying the values of patients with incurable cancer without regular treatment options will empower patients and will create more effective patient-physician communication which helps to better attune communication to the…
The aim of the study is to assess whether in women with early PPROM tocolytics improve perinatal outcome.
We hypothesize that the deformation-area curves will show an alteration in the relationship between deformation and area for the differing (pressure or volume related) cardiovascular diseases
The aim of this study is to assess the predictive value of the HowRwe questionnaire in relation to the EUROPEP questionnaire by analyzing scores acquired in Dutch GP practices. We expect that high HowRwe scores are associated with an positive…
Het onderzoek is gericht op het vaststellen van factoren die betrokken zijn bij subfertiliteit en ernstige zwangerschapscomplicaties die in het begin van de zwangerschap ontstaan. Door toename aan inzicht in de pathogenese van deze aandoeningen, zou…
The correlations between the three measurement instruments are moderate (r = 0,41 to 0,60).
A one-day-visit systematic assessment in a specialized severe asthma centre contributes to improvement in asthma control, quality of life and healthcare utilization.
this study will contribute to the implementation of shared decision making in the field of hand therapy, by mapping experiences with the application of shared decision making in current practice and by getting insight information in needs and…
1. The implementation of the Trauma-Sensitive Schools’ programme in (special) education contributes to improved student functioning. 2. The implementation of the Trauma-Sensitive Schools’ programme in (special) education contributes to enhanced…
Treating a symptomatic urinary tract infection in patients with a long-term indwelling catheter for 5 days is non-inferior compared to the standard duration of 10 days of antibiotic therapy with regard to clinical cure rate.
The primary objective of this study is to reduce the number of patients with at least one event when using the CRR (a computerised clinical descion support system) compared to the regular care. These events consist of hospital referrals, delirium,…