17983 resultaten
Histidine supplementation will lead to higher plasma ImP levels in T2D patients, but not in healthy controls and this effect is mediated by the gut microbiota.
There is no hypothesis in this implementation study, that is designed to record facilitating and inhibiting factors when an accepted and well functioning care programme is introduced in four early adopter hospitals.
Early and aggressive treatment of rheumatoid arthritis according to a strict treatment protocol results in a 70% remission of the disease within 2 years.
We expect that OT administration in PTSD patients and controls will dampen amygdala activity and increase reward sensitivity. We hypothesize to see a group by treatment interaction effect, such that the magnitude of the neural effects of OT…
The overall survival in the arm treated without chemotherapy (TNM-stage II or III tumours) is expected to be approximately 60%. Assuming an improvement in overall survival from 60% to 70% in the arm treated with chemotherapy (TNM-stage II or III…
Surgery is the standard therapy for esophageal cancer. However, 30% of the resections are irradical. It is thought that preceding chemoradiotherapy will improve the surgery results.
Fine motor skills of visually impared children will be slower and less accurate compared to normally sighted peers.
A SPT has been proposed to screen subjects with increased risk of hypersensitivity reaction to Ruconest. Subjects with RA and subjects with clinical CMA have an increased risk of hypersensitivity: although cow's milk proteins differ from rabbit…
General practitioners and nurse practitioners are not aware of the association between diabetes mellitus and limited joint mobility (LJM), and therefore do not screen diabetic patients for musculoskeletal complaints of the upper extremity.
Genestein inhibits the synthesis of heparan sulphate and can possibly slow down disease progression in Sanfilippo Syndrome patients.
Our hypothesis is that rebound thrombin generation occurs in ICU-patients after abrupt cessation of heparin treatment in terms of elevation of coagulation-markers and reduction fibrinolysis-markers; IV-weaning of heparin reduces this rebound…
The hypothesis is that all procedures look different per therapist and parent collaboration and all experiences are different. Nevertheless, there possibly will be similarities in experiences and wishes for the future.
treatment with the Straumann Bone Level Tapered implant are a reliable option for single tooth replacements in the maxillary aesthetic zone. No significant differences between patients with a preserved alveolar ridge or patients with a non-preserved…
In RA patients that achieved disease remission by treatment with the combination of a csDMARD and anti-TNF, there is a difference in (cost-)effectiveness when medication is tapered according to strategy A (csDMARD first) compared to strategy B (anti…
Atomoxetine will be effective in reducing symptoms of inattention and overactivity in children and adolescents with ASD.
What is the effectiveness of Diclofenac compared to Paracetamol over a period of two weeks and if necessarily another two weeks (consistent with the Dutch guidelines for general practitioners) in new consulters with knee osteoarthritis in the…
ACT will, compared to care-as-usual result in less admission days and more sustained contact with mental health. Moreover, life skills will be more improved possibly resulting in a higher quality of life.
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Participants from both the intervention groups will increase their protein intake more than participants in the control group.