17983 resultaten
One-stop-shop concept, using real-time in vivo reflectance confocal microscopy as diagnostic tool is non-inferior to standard of care in the surgical management of new primary basal cell carcinoma
We hypothesize that evaluation of the IFOMPT framework gives insight into the reproducibility and diagnostic accuracy of this screening tool for risk estimation of vascular complications among manual-physiotherapists
It is expected that 8 days of supplementation with the study product will contribute to an improved immune response and to increased incorporation of EPA and DHA in white and red blood cells and plasma.
Interindividual variation in antihypertensive drug response can be predicted through lifestyle, demographics and plasma drug levels.
Lipotoxicity-related cardiac abnormalities can be reversed by PPAR g agonist therapy in type 2 diabetes patients.
The nephrotoxicity caused by cisplatin is of great concern both in that it is dose-limiting and can be detrimental to the patient. Much work has been done to reduce or prevent this damage to renal cells, however to date the best approach has reduced…
A health education program for both patients and general practitioners will change behaviour by 15%.
To test the accuracy of dynamic MRI with T1 mapping in patients with CD and compare this with know parameters such as CDEIS, CRP and CDAI.
In the original study (NTR215), we assessed the 3-year risk of CIN3+ in women stratified for hrHPV and cytology at baseline. In this study, we will assess the 5-year risks. Stratification at baseline is done on hrHPV, cytology, and hrHPV genotype.…
With implementation of the AWR and APWR by the ED triage nurse we expect a reduction in the total number of radiographs requested, without missing any clinical relevant fractures. We also expect a reduction in overall waiting times at the ED and…
Victims of IPV, living in an unsafe and unhealthy situation, are faced with a broad range of physical and emotional symptoms. Standard and easy-accessible care to facilitate change into a safer situation is lacking. The project aims to launch an…
To reduce treatment-related toxicity in patients with localized prostate cancer, focal treatment is warranted. This can be achieved with MRI guided high-dose-rate brachytherapy. We expect that a single dose of 19 Gy to the tumour volume will be of…
Not applicable
Budesonide does not alter the exposure of cabazitaxel in castrate resistant prostate cancer patients.
Hearing aid fitting will reduce the tinnitus burden in patients with mild hearing loss.
1. Is a multidisciplinary cognitive behavioural lifestyle program more effective in losing weight and permanent weight loss for women with PCOS and obesity then regular care? 2. Is a multidisciplinary cognitive behavioural lifestyle program in…
Several reports have indicated that the chemokine receptor CCR5 and its ligands, escpecially CCL5 (formerly known as RANTES), may play a role in the pathogenesis of psoriasis. CCR5 targeted treatment could therefore be a therapeutic option for…
THypothesis: The integration of measurement outcomes in response to the PhenFlex challenge test will enlarge small, single differences by combining multiple but small effects on metabolism leading eventually to a measurable health difference before…
patients with diabetic cardiovascular autonomic neuropathy are more prone to hypotension during surgery and therefore require more inotropic/vaspressor medication perioperatively
Patients who receive treatment as usual (TAU) plus mentalization-based treatment for psychosis (MBT-P) will show a greater improvement in social functioning than patients who receive TAU only. This effect is mediated by an increase of social…