17983 resultaten
The hypothesis to be tested is that the outcome in arm B is better than in arm A.
Based on earlier studies it is likely that current rhDNase inhalation in children during exacerbations is relatively inefficient. We hypothesize that the efficacy of rhDNase treatment during exacerbations can be improved by targeting the peripheral…
We are interested in the workability of the non-invasive abdominal electrode patch for implementation in clinical practice. We expect to establish a reduction of use of fetal scalp electrode from 70% to 45%. Postpartum monitoring of contractions…
Severe fatigue is a common complaint after completion of breast cancer treatment with curative intent. To extend treatment options for postcancer fatigue, the efficacy of an internet therapy with minimal therapist support is examined in the current…
DHA and AA during pregnancy shall lead to a better neurological development of the baby and possibly to better mood, cognitive functioning and sleeping rhythm of the mother.
The intended research aims to evaluate whether a better suppression of adrenal androgens, so a better hormonal setting, can be achieved by changing the time of the highest dose in the morning or in the evening.
The hypothesis is that a Collaborative Care Program for patients with severe personality disorders improves quality of life and self management skills, and reduce destructive behaviour and other manifestations of the personality disorder in…
With implementation of the AWR we expect a reduction in the total amount of radiographs requested, without missing any clinical relevant fractures. We also expect a reduction in overall waiting times at the ED and a total amount of cost savings…
Repeated feedback reports in which the volume and quality of referrals is discussed will lead to fewer non-rational referrals.
In this study we will investigate the progression of IF/TA in protocol biopsies in a cohort of renal transplants, with a steroid sparing TAC-based immunosuppressive regimen in combination with either sirolimus (SRL) or mycophenolate mofetil (MMF),…
Type 2 diabetes is a major threat to human health. Disruption of the circadian timing system is associated with metabolic changes. Disturbance of the daily light and dark rhythm could contribute to this phenomenon and effects metabolic pathways. We…
Considerable health efficiency gains can be achieved by the substitution and optimization of usual perioperative care by means of e-health and ICT.
This study examines the interplay between adolescents’ peer relations and molecular genetics in predicting risk behaviors. The central question is: How do molecular genetic information and peer dynamics interplay in explaining adolescent risk…
The hypothesis to be tested is that the outcome in arm B is better than in arm A.
To determine the influence of curcumin and piperine on tamoxifen pharmacokinetics.
1) Ethical dilemmas are present in anaesthesiology. 2) Ethical dilemmas are usually not perceived or approached as such by anaesthetists. 3) There is a difference in type and occurrence of ethical dilemmas between academic and non-academic…
COPD is a common chronic pulmonary disease in (vulnerable) elderly people, that in 25% coexists with chronic heart failure. Both COPD and chronic heart failure have a high burden of disease with intermittent disease deteriorations (exacerbations)…
The aim of the present prospective cohort study is to assess the clinical and microbiological effects and patient-reported pain in the non-surgical treatment of peri-implantitis using a pocket irrigator/evacuator device
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So far no data on effective treatment for Q fever Fatigue Syndrome (QFS) are availabe. At present, it is unclear whether effective treatment for QFS is possible. The objective of this study is to assess the efficacy of two treatment strategies for…