Zoeken naar een onderzoek

Mesenchymal Stem Cells for the treatment of Crohn's Disease

It is safe and feasible to administer autologous bone marrow derived MSCs for treatment of Crohn's Disease (CD).

Minimax study; open reduction and internal fixation with volar fixed-angle plating vs percutaneous reduction and external fixation for displaced intra-articular fractures of the distal radius in the eldery

ORIF with volar fixed-angle plates and external fixation have a similar outcome as measured with the DASH score (and the Mayor Wrist Score).

Observational study.
Metingen naar de functie van de longen bij kinderen van 0 t/m 4 jaar oud: kinderen met CF en gezonde kinderen.

The measurements of overnight SpO2 and/or gas mixing and/or overnight cough might be useful in CF patients aged 0-4 years old. In this age group, standard spirometry can not (yet) be performed. As a consequence, there currently are no measurements…

Investigating new imaging criteria for non-operative treatment following neoadjuvant chemoradiation in rectal cancer patients

Combining digital FDG-PET/CT and DW-MRI imaging will more accurately predict and define response in rectal cancer patients after neoadjuvant treatment.

Forced Use in the Pirate group for children with predominant unilateral Cerebral Palsy.

A period of 6 weeks Forced Use of the more affected upper limb for children with Cerebral Palsy and asymmetric upper extremities, combined with two weeks bimanual play activities in the so called Pirate group (for 3 hours on 3 afternoons a week)…

Open lung positive pressure ventilation in neonatal respiratory distress syndrome.

We hypothesize that alveolar recruitment and stabilization (open lung) is feasible during positive pressure ventilation of preterm infants and improves gas exchange compared with conventional positive pressure ventilation.

Gelukkig ondanks pijn: Een interventie op het internet voor chronische pijn patiënten.

Are a positive psychology and a self-management intervention, equally effective in increasing quality of life and decreasing psychological distress and pain disability, in chronic pain patients, in comparison to a waiting-list control group?…

The effect of continuation of anti-platelet agents on bleeding complications after dento-alveolar surgical procedures.

Common traditional practice until now has been discontinuation of the antiplatelet therapy 7 to 10 days prior to dental surgery, but controlled prospective data in the literature to support this practice are lacking. The discontinuation of…

The clinical effects of leukocyte removal filters, cellsavers and their combination on blood transfusion and organ damage during cardiac surgery.

We hypothesize that the application of a leukocyte depletion filter for surgical wound blood will reduce organ damage and coagulation disorders through removal of activated leukocytes and other particles. We expect that the efficacy of a cell saver…

Mindfulness training in older patients with cognitive complaints [Dutch: Mindfulnesstraining voor oudere patiënten met geheugenklachten]

Delivery of a generic MBSR training to patients who visit a memory clinic with cognitive complaints, and who show no clinical signs of a cognitive disorder, is feasible.

De effecten van verschillende doseringsverhoudingen van middelen die de stolling remmen of activeren op bloedverlies tijdens hartchirurgie.

It is hypothesized that a low protamine-to-heparin ratio leads to improved hemostasis after cardiac surgery with cardiopulmonary bypass as compared to a high ratio as measured by rotational thromboelastometry, and reduces postoperative blood loss…

Castration-resistant prostate cancer registry: An observational study in the Netherlands.
Gevorderd, castratie-resistent prostaatkanker: Een observationele studie in Nederland.

The annual incidence of castration-resistant prostate cander (CRPC) in the Netherlands is estimated at 2868 patients. After development of CRPC, survival with best supportive care is not expected to exceed 12 months. Fortunately, several new…

Lichamelijke activiteit en energieverbruik van hoofdhalskanker patiënten.

This study primarily aims to explore changes in physical activity pattern and energy expenditure in head and neck cancer patients, during and after treatment with surgery with or without (chemo)radiation. The following primary null hypotheses will…

Think different: effectiveness of an online training for children with obsessive-compulsive disorder

The aim of the present study is to improve treatment for children with OCD by adding an online Cognitive Bias Modification-Interpretation (CBM-I) training as a pre-treatment to cognitive behavioural therapy (CBT). CBM-I is compared with a waitlist…

PILOT STUDY 1 'Prevention Of Malnutrition in Senior Subjects (PROMISS)'

In this pilot study among community-dwelling older adults with lower protein intake (< 1.0 g/kg/body weight), we hypothesize that personalized dietary advice will increase protein intake in close proximity of usual physical activity.

Psychophysiological stress mechanisms in chronic inflammatory diseases.

Particularly in patients at risk, the stress-management intervention affect self-reported, immune and neuroendocrine indicators of stress reactivity.

The effects of a functional fitness training in children with cerebral palsy.

Children with cerebral palsy will benefit from a functional fitnesstraining.

The ‘Together Happy!’ (‘Samen Happie!’) intervention to prevent obesity through parenting: A study among Dutch parents of toddlers

Childhood obesity is a serious epidemic in western societies. Parents are considered as a key influence in children’s weight-related behaviors. It is thus not surprising that recent interventions to prevent childhood obesity have increasingly…

Identifying the characteristics of the favorite communication partners of people with aphasia throughout their social network.

People with aphasia have problems with communicating. Because communication is very important in the society, these group suffers from a smaller social network, diminished social participation and as a result of this, loneliness, a loss of autonomy…

Dutch Antibiotics in RSV infection Trial.

Antibiotic treatment of hospitalised children with RSV LRTD has no beneficial effect on the clinical course.