7455 resultaten
Does sildenafil improve tumour perfusion?
A mathematically correct PK-PD model will be developed that describes the depressant effect of propofol on breathing with and without a background of remifentanil.
The main objective of this study is to compare upper extremity dysfunction (UED) following slender TRPCI using small bore catheters (5F) compared to standard PCI using regular size guiding catheters (6F) and conventional stent techniques at two…
DOACs are non-inferior to LMWH with regard to the risk of ICH in patients with brain cancer requiring anticoagulation.
We hypothesize that, with increased arm abduction moment loading with a constant exerted abduction force, primary arm moment generators (deltoid muscle) will have a greater increase in activation (EMG) as compared to primary arm/glenohumeral…
The null hypothesis will be that the prevalence of bruxism and TMD, in PD patients will be higher than in their peers without PD. Also, we hypothesized that factors as medication use, disease severity, psychosocial factors and lifestyle factors are…
Recurrent miscarriages is defined as three or more consecutive miscarriages prior to the 20th week of gestation. Whenever the diagnosis ‘recurrent miscarriages’ is established, an underlying cause may be identified in about 25-50% of cases. A…
The primary hypothesis for this data collection study is that there are various surrogate physiological parameters for inferring blood pressure (BP), which can be more easily obtained than the direct BP measurement. An example of such surrogate…
Chronic heart failure (CHF) is a clinical syndrome resulting from a decreased cardiac output, insufficient to maintain adequate tissue oxygenation. Eventually, inadequate tissue oxygenation will lead to pathological alterations, especially at the…
What are the motivations of women in the Netherlands to choose UC and what are their beliefs on childbirth in general and in relation to current Dutch maternity care? This study primarily aims at understanding women’s motivations in declining (parts…
We hypothesise that glaucoma patients with non-overlapping visual field defects have poorer binocular visual performance while performing complex visual tasks than would be predicted from their visual field. Knowledge on this topic is highly…
Radium-223 is the 5th treatment for metastasized castration resistant prostate cancer with a proven overall survival benefit. The improved survival of Radium-223 over placebo was demonstrated in the ALSYMPCA trial, which included a miscellaneous…
The primary objective of this study is to explore the correlation between invasive and non-invasive haemodynamic variables and monitor the effect of treatment during admission for acute decompensated heart failure. In particular to investigate…
To assess the change in voiding pattern and quality of life in children who receive BoNT-A treatment in a prospective setting.
The aim of this study is to describe the last phase of life of people with young-onset dementia. The research questions for this prospective observational study are: 1. What is the practice of end of life care in people with young-onset dementia…
During the convalescence phase of critical illness patients will enter an anabolic phase in which REE increases and there is a subsequent increased nutritional need.