514 resultaten
The overall objective of this study is to assess safety of AG-348 and provide proof of concept of the efficacy of the drug in SCD patients. Based on currently available data, we hypothesize that the benefits of treatment of sickle cell disease…
In non-COVID-19 patients with pulmonary embolism a prevalence of up to 70% of concomitant symptomatic or asymptomatic deep venous thrombosis has been reported. Physicians experience an exceptionally high prevalence of pulmonary embolism in COVID-19…
residual thyroid function is altered by short term oral antibiotic treatment in subclinical hypothyroid subjects as compared to healthy controls.
1. The primary objective of this study is to investigate whether nocebo effects on cowhage-evoked itch can be induced by verbal suggestion. We hypothesize that the verbal suggestion that the solution applied is an ‘itch solution’ will induce higher…
Patients with new-onset or recurrent AF have an altered myocardial sympathetic activity. The quantification of sympathetic activity with 123I-mIBG scintigraphy, as well as its change over time after restoration of sinus rhythm, can be used to target…
Observational study
It is expected that the use of the MFB intervention will improve subjective cognitive functioning.
With this study we aim to disentangle mindfulness and placebo effects on pain. We investigate how decentering (a core component of mindfulness) and positive treatment expectations (a core component of placebo effects) interactively contribute to…
Similar or better fixation, migration and functional outcomes compared to other existing techniques
We hypothesise that the health behaviour of pregnant women is influenced by the measures to prevent the spread of COVID-19. It is not clear however, if it is positively affected (because of having more time, providing online options, creating a…
To determine the feasibility of the measurement protocol of a large prospective longitudinal study to describe the exercise capacity and physical functioning of critical illness survivors up to 5 years after discharge from the ICU.
Our hypothesis is that critical ill COVID-19 patients suffer more from their own immune response against the virus, than from the viral infection itself. Alkaline phosphatase (RESCAP®) has proven to reduce SIRS reactions by neutralizing the…
We expect the “movement with pain” program will result in a reduction in disability, improved perceived recovery, improvement of psychological wellbeing and increase in physical condition. Moreover, we expect that a combination of the amount of…
RR with prompting results in a higher rate of self-initiated toileting and a decrease in urinary/faecal accidents. For children who do not attain continence with RR and prompting alone, an add-on restoring procedure will result in a higher rate of…
The sentinel node procedure is feasible and safe in women with a first recurrent vulva cancer
It is expected that the affected lower extremity has lower motor control than the unaffected side and in severely affected stroke patient, the motor control is lower compared to less affected stroke patients.
To test the hypothesis that apathy after STN DBS may be reversed by switching the activated contact on the DBS-electrode from a ventral to a more dorsal contact.
We expect relatives to be satisfied about the last period of life after non-operative management of the hip fracture.
Deleayed umbilical cord clamping during elective caesarean sections has short and long term benefits for the neonate, whilst not increasing the risks for mother and neonate.
It is hypothesised that both laser devices will be highly comparable