1281 resultaten
Acid-reducing drugs, such as PPIs, may profoundly decrease solubility and, as a result, (negatively) affect the bioavailability of afatinib. Since a PPI is often used concomitantly during afatinib therapy, this DDI confronts physicians, patients,…
Intravenous ketamine infusion will result in analgesia
To evaluate the anti-inflammatory effects of 3 months statin therapy on vessel wall inflammation by means of FDG PET/CT in patients with CKD.
1. Does Levothyroxine treatment for subclinical hypothyroidism give multi-modal benefits for the oldest old people with subclinical hypothyroidism? 2. Are benefits seen across a wide range of outcomes, including prevention of cardiovascular disease…
- How effective are the Acts of Kindness exercises with and without reflection compared to an active control condition and wait-list condition on mental well-being, flourishing, positive relations, gratitude, positive and negative emotions, optimism…
In this randomised controlled study, the effects of art therapy is examined on psychological functioning of patients with a personality disorder. It is expected that art therapy results in less personality pathology, more acceptance, and less…
An early mobilization program in critically ill children reduce the consumption of sedatives and opioids and the prevalence of delirium.
Inhibition of the H1 receptor will lead to an improvement of rectal sensitivity, followed by less abdominal symptoms in patients with irritable bowel syndrome.
Due to surgery and radiotherapy lymph drainage pathways in recurrent breast cancer could be altered. These aberrant drainage pathways could be detected with lymphatic mapping and sentinel node biopsy leading to a more thorough staging and possible…
Chronic cold exposure will increase: 1. Basal metabolism and facultative thermogenesis; 2. Brown adipose tissue activity and volume both in obese and diabetic subjects; 3. Skeletal muscle mitochondrial uncoupling and result in BRITE cell recruitment…
Computerized decision support (CDSS) for tailoring prevention to the local circumstances using the guidelines of the Dutch college of general practitioners has impact on preventive activities in the primary care setting
Outpatient LMHW treatment in patients with objectively proven non-massive pulmonary embolism is efficacious and safe.
In EPF, the sequential combination of mifepristone with misoprostol is superior to the use of misoprostol alone in terms of complete evacuation of products of conception, patient satisfaction, complications, side effects and costs.
- brain activation and connectivity during emotion regulation, thinking about future events, inferring on emotions of others and rest are different in patients with a recent suicide attempt compared to patient controls and healthy controls - brain…
It is safe and feasible to administer autologous bone marrow derived MSCs for treatment of Crohn's Disease (CD).
ORIF with volar fixed-angle plates and external fixation have a similar outcome as measured with the DASH score (and the Mayor Wrist Score).
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We hypothesize that the range of motion of the hallux is limited during gait in patients with hallux rigidus (HR). In addition, we hypothesize that patients with HR will compensate this loss of motion of the hallux by increasing joint motion in the…
We hypothesize that providing personalized feedback on one’s health and diet will help low socio-economic status consumers to improve their dietary pattern, and even more so if personalized dietary advice is added to the feedback. The pilot study…