1473 resultaten
Intravenous ketamine infusion will result in analgesia
The overall objective of this study is to assess safety of AG-348 and provide proof of concept of the efficacy of the drug in SCD patients. Based on currently available data, we hypothesize that the benefits of treatment of sickle cell disease…
The null-hypothesis predicts that Inlife is not feasible. The alternative hypothesis predicts that the Inlife intervention is evaluated as being feasible. We expect the alternative hypothesis to be true. Inlife will be feasible and minor revisions…
1) The knowledge of the legal aspects of health care and medical negligence/errors among medical residents is larger in the intervention group than for the control group 2) The flipped classroom model is effective as a teaching method in post…
The EuraHS-QoL questionnaire is a valid instrument to measure quality-of-life before and after ventral hernia repair.
In non-COVID-19 patients with pulmonary embolism a prevalence of up to 70% of concomitant symptomatic or asymptomatic deep venous thrombosis has been reported. Physicians experience an exceptionally high prevalence of pulmonary embolism in COVID-19…
Inhibition of the H1 receptor will lead to an improvement of rectal sensitivity, followed by less abdominal symptoms in patients with irritable bowel syndrome.
Due to surgery and radiotherapy lymph drainage pathways in recurrent breast cancer could be altered. These aberrant drainage pathways could be detected with lymphatic mapping and sentinel node biopsy leading to a more thorough staging and possible…
Computerized decision support (CDSS) for tailoring prevention to the local circumstances using the guidelines of the Dutch college of general practitioners has impact on preventive activities in the primary care setting
residual thyroid function is altered by short term oral antibiotic treatment in subclinical hypothyroid subjects as compared to healthy controls.
We expect that mp-MRI, molecular urine test and Prostate Cancer Risk Calculator may be of additional value in differentiating between significant and insignificant cancers in men with an elevated PSA in the primairy diagnosis. If so, it will result…
Outpatient LMHW treatment in patients with objectively proven non-massive pulmonary embolism is efficacious and safe.
1. The primary objective of this study is to investigate whether nocebo effects on cowhage-evoked itch can be induced by verbal suggestion. We hypothesize that the verbal suggestion that the solution applied is an ‘itch solution’ will induce higher…
Refinement of the CHIP prediction rule will lead to a more efficient use of head CT in patients with minor head injury
Patients with new-onset or recurrent AF have an altered myocardial sympathetic activity. The quantification of sympathetic activity with 123I-mIBG scintigraphy, as well as its change over time after restoration of sinus rhythm, can be used to target…
Observational study
It is safe and feasible to administer autologous bone marrow derived MSCs for treatment of Crohn's Disease (CD).
ORIF with volar fixed-angle plates and external fixation have a similar outcome as measured with the DASH score (and the Mayor Wrist Score).
It is expected that the use of the MFB intervention will improve subjective cognitive functioning.
The objectives of this pilot are (1) to test and develop an experimental setup to determine contrast sensitivity, visual field and adaptation time at high light conditions. (2) To perform a pilot study with 10 healthy subject.