2502 resultaten
Chronic cold exposure will increase: 1. Basal metabolism and facultative thermogenesis; 2. Brown adipose tissue activity and volume; 3. Skeletal muscle mitochondrial uncoupling and result in BRITE cell recruitment.
Adding prebiotics or ferments to infant formula may improve digestive comfort in infants. Therefore, the infant formula tested in this study, combining these ingredients, may contribute to improved digestive comfort. In this study it also has been…
During the cooling by a cold cap, the scalp is cooled to 4oC for a long period of time (30 minutes prior to start and up to 45 minutes after the infusion of paclitaxel). This could be of influence on the body temperature. Pharmacokinetics and…
Stand-alone internet-based Vestibular Rehabilitation (VR) and internet-based VR with physiotherapeutic support is more (cost-)effective than usual care when treating dizziness in older patients in general practice.
It is hypothesized that a low protamine-to-heparin ratio leads to improved hemostasis after cardiac surgery with cardiopulmonary bypass as compared to a high ratio as measured by rotational thromboelastometry, and reduces postoperative blood loss…
The annual incidence of castration-resistant prostate cander (CRPC) in the Netherlands is estimated at 2868 patients. After development of CRPC, survival with best supportive care is not expected to exceed 12 months. Fortunately, several new…
Based on the human milk composition, Nutricia Research has developed a new infant formula with a new fat blend, more similar to that of human milk. This new formula is currently being studied for safety and its effects on growth. The comparator used…
The effectiveness of an indicated indicated depression and anxiety prevention program ('Een Sprong Vooruit') will be tested in a Dutch sample of adolescents (aged 11-15) with high familial risk. It is expected that the adolescents who…
To investigate the impact of an open label non-mandatory switching strategy from Enbrel to Benepali on drug survival, effectiveness and safety in a controlled cohort study of RA, PsA and SpA patients in daily practice.
The beneficial effect of cold acclimation on insulin sensitivity is reproducible and the effect wil sustain for a longer period of time. Besides insulin sensitivity, cold acclimation also has beneficial effects on cardiovascular risk factors in type…
The implant stability for the GTS is equal to the Taperloc in the initial two years and also thereafter. Focus will be on proximal or distal migration of the centre of the stem, migration of the tip, wear and survival.
The intention to change behavior is related to changes in multiple physiological variables. Thermal comfort and thermal sensation are related to these physiological parameters. Furthermore, the intention of behavior is related to changes in thermal…
Exploring QOL, hope, treatment motivition, coping en locus of control of patients considering early clinical cancer trial participation.
1. The intervention is effective in reducing eating disorder symptoms; 2. There is an incremental effect of intensive/frequent support from a coach in terms of reducing ED symptoms.
1. A multidimensional lifestyle intervention, including aspects of increased awareness, motivation, self-management, diet, exercise, and a supportive environment, improves or prevents deterioration of the cardiometabolic risk factors of SMI…
The primary alternative hypothesis states that the mean relative infarct transmurality (RIT) is different in patients with (RITshock or ATP ) and without appropriate ICD intervention, i.e. shock or ATP.
To compare the recurrence rate at 1 year following Narrow Band Imaging and TURB (Arm A) with White Light Trans Urethral Resection of Bladder cancer (TURB) (Arm B) in patients with non muscle invasive (NMIBC Ta/T1) bladder cancer.