173 resultaten
We hypothesize that by using different imaging techniques, we can give a good characterization of the bone marrow microenvironment in advanced-stage myelofibrosis, before and during treatment with ruxolitinib.
H1: the exercise intervention is effective in reducing (work-related) fatigue H2: the exercise intervention is effective in improving (work-related) self-efficacy, sleep quality, work ability, cognitive functioning, and aerobic fitness.
Children aged 4 to 6 years in the intervention group who have received the GigaGaaf! intervention have a different oral health than children aged 4 to 6 years from the control group who have received care as usual. Parents of the children aged 4 to…
Informed consent procedures and information provision differs between different transplantation centers and transplantation professionals in The Netherlands. Donor knowledge and satisfaction may be influenced by the manner of information provision…
There seems to be a biphasic process of bone mineral density (BMD) changes in osetoarthritis (OA). An increased bone mineral density (BMD) and a specific distribution of BMD in the cortical of the subchondral plates and below in the trabecular bone…
We hypothesise endo/epicardial substrate homogenization in a first approach to be superior to endocardial substrate homogenization alone, in terms of recurrence on follow-up.
The hypotheses of this study are that parents at increased risk of parenting problems who receive the intervention Solid Parenting (“Stevig Ouderschap”) during the first 18 months after childbirth, will enhance their social support network and…
To analyse the diagnostic and prognostic value of plasma EV protein/miRNA and gene expression profiles of circulating cells for objectified ischemic coronary artery disease in patients with symptoms (e.g. chest pain) suggestive of coronary artery…
We hypothesize that: 1) Patients receiving an ice-lolly or chewing gum directly postoperative will have lower pain intensity scores in the 24 hours following surgery compared to no non-pharmacological treatment. 2) Patients receiving an ice-lolly or…
Primary aim: 1. To investigate whether differences exist in the mitochondrial energy generating capacity of skeletal muscle of statin users with SAMS compared to statin users without SAMS and controls (non-statin users). Secondary aims: 2A. To…
Children participating in daily sport classes will attain higher academic achievement than their counterparts who participated in the standard physical education classes incorporated in the school curriculum (1 hour/week).
We hypothesize that the active strategy leads to a better functional outcome than the conservative strategy three months after acute ischemic stroke, in patients with elevated pre-treatmen blood pressure otherwise eligible for intravenous…
In this RCT we investigate the effects of two school-based physical activity interventions (aerobic exercises versus coordinative exercises) in primary school children on executive functions and academic achievement. We hypothesize that both aerobic…
What are the motivations of women in the Netherlands to choose UC and what are their beliefs on childbirth in general and in relation to current Dutch maternity care? This study primarily aims at understanding women’s motivations in declining (parts…
•To assess the safety and tolerability of induction doses of ABP-700 and determine dosing regimens that reliably produce drug induced unconsciousness and the pharmacodynamic conditions necessary for induction of general anesthesia with ABP-700 alone…
The rationale for this study is to assess the visibility and positional accuracy of the laser marks. Combined with VLE imagery, the targeting enabled by the laser marking system could have the potential to increase the diagnostic accuracy of current…
We hypothesize that SNNS might be of great value in early esophageal cancer, especially in the treatment of high-risk early EAC (T1b-tumors). A treatment algorithm consisting of endoscopic resection of the tumor, followed by SNNS and (adjusted) LN…
Differences in the healthcare, workplace, legislative, and personal systems (see figure) as well as evaluator and patient characteristics may better explain differences in FCE results