1507 resultaten
We expect the protein synthesis rate in (avascular) femoral bone proximal to the fracture to be lower when compared to healthy femoral bone.
Good Inter-observer agreement for important markers such as bowel wall thickness and Doppler activity
It is hypothesized that physical activity will have a positive (dose-response) effect on cognitive control, measured as error processing, response inhibition and interference effect.
The overall objective of this study is to assess safety of AG-348 and provide proof of concept of the efficacy of the drug in SCD patients. Based on currently available data, we hypothesize that the benefits of treatment of sickle cell disease…
Hypotheses are that the program will have a positive effect on the health, safety, talent development and socioeconomic health inequities of youth and children in experimental neighborhoods in comparison to control neighborhoods.
Childhood obesity is a serious epidemic in western societies. Parents are considered as a key influence in children’s weight-related behaviors. It is thus not surprising that recent interventions to prevent childhood obesity have increasingly…
Implant survival rate of 90% or higher
During a contra-lateral cervical lateral glide mobilization technique, the median nerve longitudinally moves at the sites of the elbow and/or the wrist and there is a notable difference between patients and healthy controls.
Parents who receive the two-day EMDR treatment will report significantly lower trauma scores and psychological comorbidity scores post-treatment compared to the wait-list group.
Changing the context in which individuals make lifestyle choices has a sustained impact on the dietary intake and cardiometabolic health.
We want to determine the influence and safety of probenecid on sorafenib pharmacokinetics. By inhibiting the OAT6 transporter there might be a faborable effect on Hand-foot syndrome
TKR with large migration in the last 2 PO years show a larger inducible migration compared with TKR with little to no migration in the last 2 PO years
Patients improve more in upper limb function after CCT in comparison to usual care. Patients are equally satisfied with both CCT and usual care as therapy. Patients have more active minutes during CCT in comparison to usual care.
Our hypothesis is that despite advanced laboratory techniques serum levels of amylase/lipase are <3 times ULN in patients presenting with hypertriglyceridemia during acute pancreatitis.
We hypothesize that rectal NSAID prophylaxis use will have significantly risen in comparison to the 2013 survey. We hypothesize biliary endoscopists will show a significantly better risk factor recognition than general gastroenterologists. We…
What is the influence of protective gear on the performance of basic life support (BLS) by KNRM lifeboat crewmembers during a manikin simulation training
Respiratory Syncytial Virus (RSV) is still the leading cause of hospitalization of children under 5 years of age. Currently, there is no effective treatment licensed for an ongoing RSV infection. Therefore, Intravacc develops a live-attenuated…
Tacrolimus (FK506) is the main immunosuppressant that is prescribed after kidney transplantation. One of the disadvantages of Tacrolimus is the small therapeutic window. In transplantation patients therapeutic drug monitoring is routinely performed…
Based on literature we assume a 20% day 30 mortality of patients admitted to the hospital ward with COVID-19. We aim to lower this day 30 mortality to 10%.
1) In what proportion of severe hypoxic COVID-19 patients on HFNC is invasive mechanical ventilation necessary? 2) In what proportion of severe hypoxic COVID-19 patients with an DNI code on HFNC results in progressive respiratory failure or death?