6319 resultaten
Children in the intervention condition will consume (a) more water and (b) less sugar sweetened beverages after the intervention compared to the control condition.
Addition of alternative tests (TEG/ROTEM® and/or TGA) which reflect the whole hemostatic status of a patient might help recognizing the level of thrombin formation and fibrinolysis and improve care in ECMO patients and potentially reduce the risk of…
What is the contribution of the serum markers sFlT-1 and PlGF in the diagnosis and management of pre-eclampsia.
Reveal common mechanisms of compulsivity in OCD and GD and disorder specific characteristics of aspects that have been related to compulsivity: confidence in relation with preference for risky and ambiguous behavior, and (negative) outcome…
What is the prevalence of dysplasia or carcinoma in patients with Crohn's disease that undergo surveillance endoscopy with chromoendoscopy-guided confocal laser endomicroscopy?
The hypothesis is that immunization against VEGF will circumvent the specific drawbacks of the current anti-VEGF treatment modalities. The primary objectives of this study are to investigate the safety and tolerability of hVEGF26-104/RFASE and to…
The manual knee-rotation-test in 90 degree flection is reliable
18F-FDHT PET/CT is expected to be a predictor of response in patients with metastasized castration-resistant prostate cancer to be treated with enzalutamide
Crohn’s disease (CD) is a chronic inflammatory bowel disorder (IBD) with a major impact on quality of life. Mucosal healing is an important treatment outcome to prevent long term complications of the disease. Regulatory M2 type macrophages play a…
By giving high dose, radical, radiotherapy to patients with recurrent lung cancer, the overall survival can be prolonged and local control rate can be increased which can be done with acceptable toxicity for the irradiated normal tissues.
Our primary outcome is to change knowledge, attitude and managing skills of prison staff. We hypothesis that the elearning module will contribute to improve knowledge, attitude and skills
A dual mobility cup with a small size head (22 mm) is more likely to result in intraprosthetic dislocation than a bigger size head (28 mm).
To investigate whether the clinical outcome is similar after the implantation of the Endeavor Resolute stent versus the XIENCE V stent (non-inferiority test).
The hypothesis is that minimal invasive surgical ablation through video assisted thoracoscopic surgey as a primary treatment in patients suffering from (longstanding) persistent atrial fibrillation is superior to transvenous catheter ablation
Pyridostigmine will activate the parasympathetic cholinergic anti-inflammatory pathway and therefore reduce inflammatory signs and symptoms in patients with complex regional pain syndrome.
A switch to thrombininhibitor dabigatran or addition of tranexamic acid to the factor Xa inhibitor may be effective in women who experience heavy menstrual bleeding during anticoagulant treatment with factor Xa inhibitors.
Exploratory study to develop hypotheses
1. Repetitive Transcranial Magnetic Stimulation (rTMS), Transcranial Direct-Current Stimulation (tDCS) and Behavioural Activation Therapy (BAT) following rTMS will reduce feelings of apathy, increase goal directed behaviour and might be beneficial…
The effectiveness of school-based ('Op Volle Kracht') and computerized ('SPARX') depression prevention programs will be tested in a Dutch sample of adolescent girls with elevated depressive symptoms. The programs will be tested…
This study will test the hypothesis that Sevoflurane attenuates oxidative damage, complement, enothelial, thrombocyt and neutrophil activation and inflammation to human ischemia reperfusion injury of the myocardium.