25 results
To define the amount of dietary protein required to optimally stimulate post-exercise muscle protein synthesis in the older population.To assess whether co-ingesting 1.5 g of free leucine (contained within 15 g dairy protein) along with 15 g protein…
To further characterize the transport of phenylalanine and other large neutral amino acids across the blood-brain barrier in PKU patients with high and low brain vulnerability to elevated blood phenylalanine concentrations, we will investigate…
1. to determine whether the oxidation of BCAA (leucine) is impaired in patients with T2DM and in humans at risk to develop T2DM (first degree relatives). 2. to investigate whether an altered leucine oxidation in muscle is associated with insulin…
To investigate whether twice daily local (calf muscle) NMES attenuates muscle loss during 2 weeks of unilateral ankle immobilization due to an ankle fracture.
To evaluate the safety, tolerability, protein accretion, amino acid plasma levels and long-term outcome of Neoven compared to Vaminolact in preterm infants with a birth weight from 800 g to less than 1500 g and with a gestational age from 25 weeks…
To investigate the effects of 5 days of one legged knee immobilization with or without daily NMES on quadriceps CSA, lean mass and muscle fiber characteristics.
Primary: To measure the effect of a high protein diet on whole body protein synthesis and -breakdown, as well as on net whole body protein balance and production of urea in children after cardiac surgerySecondary: To measure the effect of a high…
Primary Objective: To provide evidence for the efficacy of wheat protein and wheat protein hydrolysate when compared with milk proteins as a dietary protein to stimulate postprandial muscle protein synthesis in vivo in healthy older humans.…
The primary objective of this study is to investigate the effect of a single meal-like amount of protein with or without fat on postprandial muscle protein synthesis in healthy elderly men. Furthermore, as a secondary objective, we will assess…
The primary objective of this study is to investigate the effect of a meal-like amount of dietary protein prior to sleep on postprandial muscle protein synthesis in healthy young and elderly men, following exercise, during the night. Furthermore, as…
To investigate whether elderly individuals lose muscle mass at a greater rate than young individuals during 5 days of one legged knee immobilization, and whether dietary protein supplementation can alleviate such muscle loss in the elderly.
STUDY 1: To investigate the impact of prior ingestion of a single high protein meal on the normal obligatory increase of muscle protein synthesis rates after protein intake and physical activity in healthy young men. STUDY 2: To investigate the…
To gain a more complete scientific understanding, it is necessary to examine whether an adaptation does in fact occur after habitual high or low amounts of protein intake with regard to the anabolic response to subsequent protein intake. In the…
Overall Objective: To define the properties of whey, casein, milk protein, as well as soy protein with and without additional leucine to augment post-exercise muscle protein synthesis when co-ingested with a carbohydrate containing recovery drink.…
To define a dose-response relationship after intrinsically labeled milk protein ingestion on myofibrillar and mitochondrial muscle protein synthesis after a single bout of endurance exercise.
To investigate the effect of preoperative protein supplementation on Hoffa*s fat pad, synovium, tendon, bone, muscle, ligament, menisci, and cartilage protein synthesis of the OA knee.
To assess the impact of short-term forearm immobilization on forearm muscle glucose uptake and amino acid net balance and kinetics of individuals with T2D compared with a control group with normoglycaemia.
To examine the effect of a single session of whole-body NMES, with or without subsequent protein intake, on whole-body protein turnover
We aim to determine the effects of collagen supplementation on biomarkers of collagen metabolism in the two weeks following total hip arthroplasty in older adults with osteoarthritis.
Primary:• To evaluate the efficacy of PTC923 in reducing blood phenylalanine (Phe) levels in subjects with phenylketonuria (PKU) as measured by mean change in blood Phe levels from baseline to Weeks 5 and 6 (ie, the average of each respective…