594 results
The main purpose of this study is to find out whether EMDR is a safe and effective treatment to reduce the symptoms of PTSD in people with mild intellectual disability and borderline intellectual functioning. In addition, it is expected to reduce…
The main objective is to determine whether the administration of allogeneic serum micro eye drops using the mu-Drop device is non-inferior to the conventional sized drops in terms of effectiveness and safety.
Calibration of the mitochondrial oxygen tension technique in the human skin
Gaining an objective insight in muscle fatigue during exercise for patients with FSHD by 1. comparing the timing of change in sEMG amplitude and sEMG median frequency, to gas exchange variables, heart rate, work load and blood lactate levels during…
This project aims to determine the validity of a home-based continuous bradykinesia assessment using free typing behaviour analysis. Secondarily, we aim to capture the presence of sequence effect in Parkinson's Disease patients using a computer…
2.1 Primary objectives2.1.1 Cross-sectional part• Technical evaluation of the functional and structural outcome measures to support a biomarker qualification by regulatory authorities and payers. 2.1.2 Longitudinal part • Assessment of prognostic…
We hypothesize that verapamil reduces progression from paroxysmal to persistent AF, improves rate control, exercise tolerance and quality of life and reduces costs compared to metoprolol.
[1] To develop robust assays for quantification of novel CSF/blood biomarkers of CAA.[2] To determine the contribution of CAA to cognitive decline in dementia and ICH patients, using CAA-specific biomarkers
The aim of this study is to investigate the effects of DMF (Tecfidera) on the association between fatigue and fatigability measures in pwRRMS starting with DMF medication.
The aim of this pilot study is to assess the effect of low intensity mastication training in patients with a mitochondrial disease on masticatory performance, efficacy, endurance, bite force and the feasibility of this training .
To investigate associations between IBD severity, ASCA titer, microbiota composition and C. albicans strains present in feces.
a. To investigate the phenotype and function of immunological cells present in endometrial and peripheral blood of women with a history of recurrent miscarriages and women without any known pregnancy complications.b. To investigate the association…
Optimise post PVI management using ambulant continuous patient-driven eHealth monitoring after catheter ablation in the treatment of atrial fibrillation.Primary Objective:1) Determine the effect of eHealth on clinical management, outcomes and…
The main objective is to identify the source of the *musician effect*, particularly for speech perception. The underlying processes involved and individual differences in different groups of participants in speech and music perception, both in quiet…
To compare the level of the sIL-2R between patients who are referred to the Center for Pain Medicine with a suspicion of CRPS but do not fulfill the new IASP Clinical Diagnostic Criteria for CRPS and those who do fulfill the new IASP Clinical…
Addition of Partner for Change Outcome Management System (PCOMS) to individual treatment will result in a significant decrease of drop-out compared to individual treatment without PCOMS in a forensic outpatient clinic in the Netherlands. A sub-…
The development of a computer aided detection (CAD) system might be able to assist endoscopists in the recognition and subsequent characterization of early Barrett's neoplasia, thereby improving efficacy of BE surveillance.
Maternal and neonatal vitamin D level play a role on dental development in childhood
We hypothesize that depletion of carnitine occurs during infusion of oxaliplatin, due to increased renal loss. This secondary carnitine deficiency may contribute to the development of CIPN.
We hypothesise that the diet over time has become healthier and more sustainable. Our current study was set up to (1) identify the differences in food consumption and nutritional quality over the course of 20 years in the Netherlands using the…