21 results
The primary objective of the study is to determine the gain in effectiveness of TE compared with P when applied to remove excess iron during maintenance therapy of HH patients.
In this study we will be looking at the effects of the different administration routes on release of satiety hormones by the small intestine.
The levels of performance decrement for the three blood alcohol concentrations will serve as a historical control for comparing the effects that will be observed with psychoactive drugs in future trials. This will make the results of these future…
Primary:* To investigate the safety and tolerability of the co-administration of GSK598809 at175 mg and ethanol in healthy volunteers.* To examine the potential pharmacokinetic interactions between GSK598809administered at 175mg and ethanol in…
1. To test feasibility of mannitol inhalations in a Dutch pulmonary out-patient clinic.2. To compare time and costs involved in measuring airways hyperresponsiveness by methacholine to mannitol
To investigate the difference between two meals (high in protein vs. high in carbohydrates) on the endothelial function?
To study the bioavailability of cocoa polyphenols incorporated into a food product. The food product is a soy-based drink to which cocoa powder is added. To compare the bioavailability of cocoa polyphenols incorporated either into a soy drink or…
The major research question is:Does a low-GI food product improve in healthy and obese men postprandial plasma concentrations of inflammatory markers as compared to a high-GI product?Major null hypothesis, H0:In healthy as well as obese men, a low-…
We hypothesized that FFA loading could impair mitochondrial function and that the potency of FFA to disturb mitochondrial function and glucose uptake would depend on the degree of desaturation of the fatty acids infused.
Paricalcitol induce a more effective reduction of the PTH level compared to alfacalcidol at hemodialysispatients with secondary hyperparathyroidism
Objective: To compare endoscopic pancreatic fluid collection drainage using a standard oblique-viewing US endoscope versus a prototype forward viewing ultrasonic endoscope with emphasis on ease of endoscopic drainage measured by procedural time.
The 3 new developed prototype electric brush heads (A,B,C) remove 15% more plaque compared to a EB17 brush head
We hypothesize that oral glucose intake and consequently the endogenous induced hyperinsulinemia will lead to insulin-induced microvascular dilatation in healthy normotensive subjects. Furthermore, we suggest that the insulin-mediated microvascular…
What is the effect of carbohydrate infusion on food choice, food intake, satiety, hormones, dependent on the time of day and segment of the small intestine?
High-intensity stress reduces cognitive performance (visuo-spatial learning) both for immediate and delayed recall.
Investigate whether DWIBS is effective for colorectal cancer screening.
We hypothesise that increasing the luminal surface exposed to the emulsion will lead to a decrease in hunger and food intake, but that otherwise, the ileal infusion will have the greatest impact on these parameters.
This study is designed to study the contribution and quantification of norketamine for its analgetic and psychomimetic effects
Long-chain triglyceride (LCT) emulsions with very small droplet sizes (fine emulsion) will lead to enhanced postprandial satiety and reduced energy intake in a subsequent meal, as compared to LCT emulsions with relatively large droplet sizes (coarse…
Gravity compensation in addition to intensive exercise therapy will result in a greater improvement in upper extremity function compared to intensive exercise practice without gravity compensation.