85 results
The main objective of this study is to assess the effect of an acute cardiovascular event on the local and the systemic inflammatory state in humans with AMI as well as the reversibility of these effects after 3 months.
Explore difference in perforating artery pulsatility index between two patients groups with small vessel disease (history of lacunar infarct and deeply located haemorrhage) and healthy controls.
To detect ophthalmic differences between patients and controles. To detect (early) changes in the retina in (pre)symptomatic RVCL disease carriers, in order to find a *biomarker* for disease stage and progression.
Primary Objective: To assess which measures of microvascular function on 7T MRI are affected in patients with CADASIL, relative to controls.
[1] To develop robust assays for quantification of novel CSF/blood biomarkers of CAA.[2] To determine the contribution of CAA to cognitive decline in dementia and ICH patients, using CAA-specific biomarkers
In this study we aim to investigate the presence of CAN in diabetic patients scheduled for elective major abdominal and thoracic surgery and its relation with perioperative hemodynamic changes.
The aim of the current study is to identify couplings of muscle activation patterns (muscle synergies) in reaching movements in stroke patients. Insight in the motor control of stroke patients can contribute to improve the disabled arm functioning…
The primary objective of this study is to determine the prevalence of white matter lesions and subjective/objective neurocognitive functioning in women several years after pregnancy compared to nulliparous women The secondary objective is to…
The aim of this study is to compare the integrity of the corticospinal tract and cortical reorganization of shoulder girdle muscle representations in chronic stroke patients with and without GHS as well as healthy controls.
a. To establish the effects of (1) body weight support (2) treadmill speed, and (3) level of guidance/ movement support, on the neuromuscular control of the lower extremities in patients with post-stroke hemiparesis, and to determine possible…
To determine the incidence of hypopituitarism in patients after SAHTo identify neurological parameters that predict hypopituitarism after SAHTo determine the value of a Ghrelin test shortly after SAH, to identify subjects with GHD.To determine the…
To detect ophthalmic differences between patients and controles. To detect (early) changes in the retina in (pre)symptomatic HCHWA-D disease carriers, in order to find a *biomarker* for disease stage and progression.
Evaluate the patients experience and progression with robot assisted arm training exercises, and monitor changes over time on arm capacity tests and quality of movements that closely match daily tasks.
Measuring the thickness of the microvascular glycocalyx, and make a comparement between lacunar stroke patients and healthy controls.We also compare glycocalyx between patients with and without concomitant silent signs of cSVD on brain MRI.
The aim of the study is to answer the following questions:On which measures do patients with aphasia seem to differ from controls matched on age and country of origin, in the analysis of the spontaneous speech according to the guidelines of the ASTA…
(1) Evaluate whether stroke patients differ from healthy controls on the experience and the course of subjective cognitive complaints during the first two years after stroke;(2) Evaluate potential predictors for cognitive complaints during the first…
- To detect carotid and aortic plaque morphology and long term plaque behaviour in patients with cerebral and cardiac end-organ damage (NSTEMI / STEMI and TIA / CVA) with 1.5T MRI-derived virtual histology and relation to biomarkers.- To correlate…
The main objective of this study is to determine if the SPC has added benefits in optimising risk factors to prevent recurrent stroke, as compared with secondary prevention performed by the GP.
Primary objective: The general aim of this study is to elucidate the role of the glycocalyx in the pathogenesis of DCI in SAH and to study the effects of magnesium on glycocalyx volume.Main objectives of this proposal are:- To assess whether the…
The objective of this study is to assess the influence of the executed motor paradigm on associations between brain activity patterns and recovery after stroke. In addition the role of spinal cord integrity in recovery will be assessed.