176 results
To investigate whether sodium and potassium mutations are found in a cohort of patients with small fiber neuropathy, painful diabetic neuropathy (versus diabetes patients with no or only minor symptoms) and in patients with breast, ovarium or…
The primary objective of this study is to assess whether the efficacy of ocrelizumab given as two dose regimens of 600 mg (given as 300 mg infusions on days 1 and 15 and 600 mg infusion in the following cycles) or 400 mg (given as 200 mg infusions…
The above anounced studies suggest that some abnormalities in the Wnt pathway can be expected to affect development and function of the brain, potentially leading to recognizable behavioural phenotypes. Given the key role of APC in the Wnt pathway,…
To assess whether the use of RFIB instead of LCNB increases the probability of a definitive preoperative histological diagnosis in women with suspicious mammographic breast lesions. assess the *RFIB success rate*, defined as the proportion of…
The first aim of this study is to determine the prevalence of cognitive impairment in COPD patients compared with persons without COPD and to compare cognitive functioning between patients referred by their general practitioner, patients referred by…
1. To characterize and compare RV myocardial structure, contraction patterns, and functional capacity of (A) PH patients (group 1 or 4, the latter are to be inoperable), (B) patients with pressure overloaded RV due to CHD and (C) healthy controls. 2…
The purpose of this study is to evaluate whether thyroid hormone replacement therapy in type 2 diabetic patients suffering from overt hypothyroidism will improve muscular mitochondrial function, lower ectopic fat accumulation in muscle and liver,…
Our primary objective is to investigate the development of structural and functional connectivity in autism and ADHD in comparison to the typical development of connectivity. A secondary objective is to investigate the effects of ADHD and autism…
2. STUDY OBJECTIVESSpecific Aim 1. To determine whether Tako-Tsubo cardiomyopathy is associated with hyper reactivity of the neurohormonal and cardiovascular systems. Hypothesis 1: Patients with a clinical history of Tako-Tsubo cardiomyopathy have…
Our primary objective is to identify the brain networks involved in tremor generation in homogeneous groups of ET patients. In addition we will investigate the differences on a behavioral level during goal-directed movements between ET subgroups and…
The focus of this present study will be to better understand the mechanism of ONS in MICCH. The primary objective of this study is to investigate the putative differences in rCBF at 6 months follow-up compared to baseline between responders of ONS…
The aim of this project is to elucidate the mechanisms underlying one of the most incapacitating psychiatric disorders, psychosis. Despite antipsychotic treatment, up to a third of patients with psychotic illness continue to experience significant…
Identification of the underlying genes of MMIHS
Assess raytracing algorithms in determining the refractive properties of the eye. This method is also applied to cataract patients and, therefore, a secondary objective is to determine the effects of surgical incisions on ocular refractive…
Primary Objective: Our main goal is to contribute to the identification of an attentional profile of the paediatric TBI population, by analysing the quality and efficiency of alerting, orienting, executive and sustained attentional functioning. This…
BODY SCHEMAThe primary objective of the current study is investigating whether AN patients and controls differ in body schema. The first secondary objective of the current study is investigate whether there is a relation between body dissatisfaction…
The proposed phase II study will test the hypothesis that preventive swallowing exercises (PSE) during treatment will reduce the incidence of swallowing dysfunction among patients with HNSCC treated with curatively intended (CH)-RT using SWIMRT. As…
Measuring the brain activity in patients with chronic WAD and compare the results with those obtained in healthy volunteers. The goal of this research is to better understand the cause of chronic WAD and how to better treat the WAD-patients.
The aim of this study is to explore the prevalence of HAND in people living with HIV.
By means of this in vivo study, we try to non-invasively get insights into the pharmacokinetics of PPD applied to the human skin. By studying penetration rate, penetration depth, allocation to different skin departments (stratum corneum, epidermis,…