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PReoperative Optimisation of Modifiable rIsk factorS in surgEry of the Pancreas:
the implementation of best practice before pancreatic resection

To investigate whether implementation of a best practice program for preoperative optimisation of patients with a focus on screening, assessment, and intervention of 8 potentially (partly) modifiable risk factors (low (aerobic) fitness level,…

Prevention of PostAmputation Pain with Targeted Muscle Reinnervation (PreventPAP trial): A national, multicenter, randomized, sham-controlled superiority trial, comparing standard neurectomy with targeted muscle reinnervation in amputations of the lower extremities.

To compare postamputation pain (phantom limb pain and residual limb pain) one year postoperatively in patients receiving a lower extremity amputation with standard neurectomy versus those who received targeted muscle reinnervation.

Neuroimaging biomarkers in Huntington*s Disease after 16 years of disease progression

Our primary objective is to compare neuroimaging markers on a 3T MRI-scan with the MRI-scans that were performed during TRACK-HD in 2008-2011. We will assess the following neuroimaging markers, starting with the most important marker: 1. Structural…

EPITHESIS VERSUS PROSTHESIS IN POST-PHALLOPLASTY TRANSGENDER PEOPLE

1. To generate initial data on whether a penile epithesis (ElatorTM) is a potential alternative to a penile prosthesis (ZSITM 475 FtM) in post-phalloplasty transgender individuals. 2. To assess participcant and partner expectations and experiences…

Development and validation of a psychological measure and derived short screener to
estimate the risk to develop personality disorders based upon the taxation of ultra-high risk
domains

The prognostic accuracy of combining these four criteria to predict the later development of personality disorders (with/without psychosocial breakdown) is investigated in a longitudinal study. From this, a selection of items with the strongest…

YOD-RiSoCo: Social Cognition and Risk-taking Behaviour in Patients with Young-onset Dementia

The overarching aim of this study is to develop new, sensitive measures for aspects of social cognition (emotion experience, empathy and affective theory of mind), that will contribute to a better and earlier diagnosis of specific subtypes (the…

aCcelerated erAS carE for minor and major liver surgery: the CHASE liver study

The aim of this study is to investigate the feasibility and safety of an accelerated protocol for patients undergoing liver surgery compared to a retrospective cohort of patients who followed the standard ERAS care for liver surgery. In this…

Hand function impairment in systemic sclerosis: Outcomes, Mechanisms and Experience (HANDSOME) study

Primary Objective: Determination of risk factors for hand function impairment in systemic sclerosis (SSc) patients with early disease, very early disease and established hand impairment (contractures) at 2 years follow-upSecondary Objective(s):-…

Assessment of the critical unit (microcirculation and mitochondrial function) in pre-operative screening.

To ascertain differences in mitochondrial and microcirculatory parameters between healthy older adults (> 65 years and ASA1-2) and more vulnerable elderly patients (> 65 years and ASA 3-4).

The use of MRI-scans to assess velopharyngeal insufficiency in cleft palate patients

The key objective of this study is to determine the clinical significance of using MRI scans as a diagnostic tool to assess velopharyngeal insufficiency in cleft palate patients.

Growing Up Together in Society: Amsterdam High-risk Antisocial Cohort

The current study describes the Antisocial High-Risk Cohort (i.e., WP3, a sub-project) of the larger Growing Up Together in Society Project (see appendix A), which has the aim to predict and understand behaviour that negatively affects society:…