271 results
The purpose of this study is to test how well a new vaccine works to protect against shingles in people after they have received a transplant with their own blood stem cells.
The purpose of the study is to test whether a centre-wide policy of incremental antibiotic therapy will reduce arrhythmia device infection in patients undergoing arrhythmia device procedures compared to a policy of conventional antibiotic…
This study aims to determine whether the ILC populations differ in the lungs of different phenotypes of asthmatic patients and healthy subjects and how these cells are regulated by bronchial epithelial cells. Furthermore we want to study how this is…
The objective of this study is to obtain the absolute bioavailability of voriconazole in critically ill ICU patients.
(i) to determine specificity of Q-detect* for registration purposes. (ii) to design a decision tree for follow-up of patients with a positive Q-detect* and
In this exploratory pilot study, we aim to investigate the role of immune activation in osteoporosis in HIV-infected patients on HAART with proven osteoporosis/ osteopenia in comparison to HIV-infected patients on HAART without osteoporosis/…
The aim of this study is to determine whether the presence and the extent of periodontitis are independently related to the presence and extent of coronary calcification.To determine if periodontal treatment has an positive effect on the…
The aim of this study is to explore the prevalence of HAND in people living with HIV.
To evaluate the effect of chemotherapy on the serological and cellular immune response to influenza virus vaccination in patients with breast or colorectal cancer in order to establisch the optimal timing of vaccination during treatment with…
The aim of this study is to create a prognostic model enabling the clinician to predict the outcome of a septic episode. Furthermore, by getting more insight in the pathophysiologic proces of sepsis, we could discover new possible targets for future…
The primary objective is to explore the association between peripheral T-cell activation and apoptosis and hepatic fibrosis in various underlying liver diseases. Secondary objectives are 1) to investigate whether level of T cell activation and…
To determine the presence of ACPAs in patients with generalized severe periodontitis. Second objective is to assess RA development of ACPA positive periodontitis patients in the future.
Determining the impact of freezing PBMC on the test result of the IGRA.
The objective of this study is to gain insight in HIV infected children in the AMC in:.- the prevalence and clinical signs of livertoxicity - an association between the different compounds of combination anti-retroviral therapy (cART) and…
To gain insight in the humoral and cellular immune response of people with risk factors for chronic Q-fever after vaccination against Q-fever and of people who have had a natural infection or have a chronic infection.
Primary objectives:- Evaluation of the value of mBL as a diagnostic tool for bacterial endocarditis.- Evaluation of the value of mBL as a monitoring tool during treatment for bacterial endocarditis.- To obtain data on the kinetics of mBL related to…
To examine neurocognition in 100 HIV1 seropositive patients on chronic effective cART using three different tests: the Montreal cognitive assessment (MoCA) , the International Aids Dementia scale (ADS) and extensive neuropsychological testing of…
The primary objective is to quantify the LIN AUC0-12h increase after addition of 250 mg, or 500 mg CLA compared to baseline (0 mg CLA). The secondary objectives are to describe the LIN and CLA pharmacokinetic parameters and to assess short-term…
Primary Objective: To determine T cell response to Coxiella burnetii antigens using an ELISPOT interferon gamma release assay in patients with different clinical outcomes after acute Q fever
The aim of the study is to explore the prevalence of HAND in people living with hiv.