51 results
To explore and optimize the usability of Doppler-OCT scanning of conditions affecting any of the retino-choroidal layers.
Primary: To explore the diagnostic value to distinguish PAF and MSA of a variety of tests: corneal confocal microscopy optical coherence tomography (OCT) to measure the retinal nerve fibre layer thickness and total macular volume, corneal…
Primary Objective: to derive iPSCs from patients with a variety of diseases caused by genetic mutations or genetic predisposition to disease or of unknown origin. The cells will be propagated and differentiated into a variety of somatic cell types…
Are changes in cognitive functioning related to structural changes in the brain in patients with type 1 diabetes mellitus. How are these changes related to diabetic complications like duration of chronic hypoglycaemia, disease duration and presence…
Assess the quality and applicability of smartphone assisted and handheld fundus photography, compared to standard fundus photography. Photographs will be taken in non-mydratic and mydriatic conditions.
Assess raytracing algorithms in determining the refractive properties of the eye. This method is also applied to cataract patients and, therefore, a secondary objective is to determine the effects of surgical incisions on ocular refractive…
Both RCTs and long-term follow-up studies are required to establish optimal fetal management and provide clinicians a better understanding of the impact of these early interventions on child development in order to improve the quality of antenatal…
To detect ophthalmic differences between patients and controles. To detect (early) changes in the retina in (pre)symptomatic HCHWA-D disease carriers, in order to find a *biomarker* for disease stage and progression.
The objective of this study is to determine the optimal background light intensity for the examination of the visual field with a perimetry test and to confirm the de Vries-Rose, Weber's and Ferry-Porters law in patients with glaucoma.
To evaluate whether straylight assessments [log(s)] can contribute to develop/refine the decision tree for the indications AC-PIOL, RLE or CE.
To investigate inter-examiner variability of the alternate prism and cover test (APCT) measurements of ocular deviation at near and distance fixation, and to compare variability between adults/teenagers and children.
To investigate the extent to which performance measurements in a driving simulator discriminate between glaucoma patients and a control group.
Primary Objective: To compare the quality of fundus photographs taken by (1) the Optoscamera in miosis and (2) the current camera in mydriasis.Secondary Objective: To compare the quality of fundus photographs taken by (1) the Optoscamera in miosis…
The goal of this study is the development of a clinically verified functional imaging technique of the retina.
To demonstrate that CLT is more sensitive for keratoconus detection compared to other corneal topography methods.
We want to assess the diagnostic performance of retinal nerve fiber layer (RNFL) thickness, macular ganglion cell layer (GCL) thickness, lamina cribrosa thickness and choroid thickness around the optic disc measured with SD-OCT in differentiating…
Primary objective: To evaluate change in RNFL thickness in RRMS patients followed for up to 36 monthscompared to a group of reference subjects (without neurologic or ophthalmic disease) todetermine whether the technology is sufficiently sensitive to…
The primary study objective is to assess whether TCS in cataract patients is a predictor of postoperative VA and if so, whether it is a better predictor than currently routinely used measurements, as represented by preoperative VA measurement…
The current study seeks to explore the SDOCT potential in a large group of patients in a clinical setting, and to compare it to existing, standard techniques.
To obtain clinical data from normal individuals to establish significance limits for the GDx RNFL measurements using the ECC method and to collect GDx RNFL measurements in subjects with early, moderate and advanced glaucoma using the ECC method to…