31 results
The primary objective is to study glaucomatous structural brain changes in a longitudinal manner, and how it relates to visual functional loss and glaucomatous retinal changes over time.
The primary objective is the degree of IOP lowering after trabeculectomy with adjuvant Ologen® implantation, in comparison to trabeculectomy with mitomycin-C. Secondary objectives are peroperative and postoperative complications, and postoperative…
The objective of this study is to determine the optimal background light intensity for the examination of the visual field with a perimetry test and to confirm the de Vries-Rose, Weber's and Ferry-Porters law in patients with glaucoma.
To investigate the extent to which performance measurements in a driving simulator discriminate between glaucoma patients and a control group.
To demonstrate that externally induced increases in epipalpebral pressure (EPP) relate to clinically significant increases in IOP, and to determine posture dependency of EPP. To determine the effects of protective goggles on EPP under these…
In the present study, we will investigate if a monocular visual field defect - due to primary open angle glaucoma - influences the anatomical integrity of the visual pathways.
We want to assess the diagnostic performance of retinal nerve fiber layer (RNFL) thickness, macular ganglion cell layer (GCL) thickness, lamina cribrosa thickness and choroid thickness around the optic disc measured with SD-OCT in differentiating…
The current study seeks to explore the SDOCT potential in a large group of patients in a clinical setting, and to compare it to existing, standard techniques.
To obtain clinical data from normal individuals to establish significance limits for the GDx RNFL measurements using the ECC method and to collect GDx RNFL measurements in subjects with early, moderate and advanced glaucoma using the ECC method to…
To demonstrate that externally induced increases in subpalpebral pressure (SPP) relate to clinically significant increases in IOP, and to determine posture dependency of SPP. To determine the effects of protective goggles on SPP under these…
The primary objective is to assess the IOP and MAP in sitting and side lying position in healthy subjects and in patients with NTG.
To determine the contrast sensitivity, visual field and adaptation time at high light conditions.
The objective of this study is to determine the light and dark adapation time and contrast sensitivity in changing background light conditions.
The first aim of this study is to evaluate a number of new perimetric methods regarding their ability to detect glaucomatous visual field defects without being stressful or difficult for older participants. In this first study, both controls and…
The main objective is to compare motion perception thresholds in glaucoma patients with healthy subjects as a function of oscillation frequency and luminance.
To examine the OcuDrive test package in glaucoma patients and healthy controls in relation to fitness to drive. The main objective is to find the tests from the package that discriminate best between fit and unfit drivers.
The aim of this study was to test these biomarkers of NO in glaucoma patients both with and without tinnitus. The objective was also to replicate findings from a previous study performed in Amsterdam, a collaboration between our research group and…
To determine the diagnostic performance (sensitivity, specificity, and area under the ROC curve) of the current eye-movement based perimetry techniques, SONDA and BulbiCAM, as potential screening instruments for glaucomatous VF defects in ophthalmic…
Main objectives: 1. Determine whether the POAG patients with low values of the blood mtDNA copy number have a low mtDNA copy number and low mitochondrial function in skin fibroblasts, using in vitro assays of mitochondrial function.2. Explore the…
1. Optimize the EMC-test*s potential to predict the SAP-parameter Mean Deviation (MD), based on simulated visual field defects in healthy observers.2. Refine the EMC-test*s potential to predict the SAP-parameter MD in patients.