760 results
The purpose of this research line is to assess whether measures acquired with advanced MR neuroimaging can be used as neuropathological markers for the early diagnosis of dementia and differentiation between AD and FTD. For each project, the…
To evaluate the long term changes in quadriceps muscle function in patients with PPS in comparison with control subjects. To correlate changes in muscle strength, functioning and symptoms with changes in motor unit size. To evaluate long-term…
- To confirm findings in previous studies regarding the loss of functioning motor units in the first day after acute stroke. - To study peripheral nervous system excitability in order to be able to formulate a more detailed hypothesis regarding the…
The aim of the study is to answer the following questions:On which measures do patients with aphasia seem to differ from controls matched on age and country of origin, in the analysis of the spontaneous speech according to the guidelines of the ASTA…
1) Identify and further explore the structural and functional brain alterations in ALS patients, PSMA patients annd PLS patients in comparison to healthy controls and ALS mimic sydromes, both cross-sectional and longitudinal; 2) Explore anatomical…
The main objective of the study is to achieve knowlegde on change in seizure semiology with age in children with partial epilepsy and to improve the understanding in the cause and consequence of this change, in relation to changing functional…
(1) Evaluate whether stroke patients differ from healthy controls on the experience and the course of subjective cognitive complaints during the first two years after stroke;(2) Evaluate potential predictors for cognitive complaints during the first…
Databases with multimodal brain imaging data (FDG-PET, VBM, DTI, ASL and resting state fMRI) will be created. From these data image features will be extracted, to be used to create a supervised classification method for associating brain patterns to…
- To detect carotid and aortic plaque morphology and long term plaque behaviour in patients with cerebral and cardiac end-organ damage (NSTEMI / STEMI and TIA / CVA) with 1.5T MRI-derived virtual histology and relation to biomarkers.- To correlate…
Primary Objective: To relate the ability to react in time to postural perturbations to set-shifting performance in Parkinson*s disease patients.Secondary Objective: To investigate the difference in set-shifting stepping responses between PD and…
To clarify the aetiology of CTS and prognostic factors for the development of CTS.
Primary objectiveTo determine whether a second IVIg dose in GBS patients with a poor prognosis improves functional outcome after 4 weeks.Secondary objectives To investigate whether: - a second IVIg dose in GBS patients with a poor prognosis improves…
The main objective of this study is to determine if the SPC has added benefits in optimising risk factors to prevent recurrent stroke, as compared with secondary prevention performed by the GP.
Objectives- We want to study time-dependent activation in neuronal networks related to pain, vigilance and autonomic functioning in migraine patients during different migraine phases (including premonitory phase);- We want to correlate these changes…
The objective is to describe the nature and underlying (neuromuscular en biomechanical) factors of dysphagia in different neuromuscular diseases in relation to different consistencies of food. Identifying the contributing factors are starting points…
The goal of this project is, in co-operation with the TU-delft, to develop a new diagnostic tool to discriminate dystonic muscles from healthy muscles contracting compensatory. This would enable us in the future to identify dystonic muscles more…
To set up a repository of genetic material from a large group of well phenotyped people with epilepsy patients to allow the case control association studies, and families for linkage studies, to analyze and detect genetic risk factors for epilepsy.
Primary objective: The general aim of this study is to elucidate the role of the glycocalyx in the pathogenesis of DCI in SAH and to study the effects of magnesium on glycocalyx volume.Main objectives of this proposal are:- To assess whether the…
To determine the influence of a pure sensory polyneuropathy on balance correction in light of the first trial response and in light of multiple succesive identical perturbations, compared to healthy control subjects.
To study the inflammatory response (induration) to intracutaneous Candida albicans in healthy individuals, patients with diabetes without polyneuropathy, patients with diabetic polyneuropathy and patients with a history of Charcot neuro-…