113 results
W want to investigate the influence of a mutaion in the MH allel on the HPV and the normal reaction of MH patients to hypoxia
To fully characterize skeletal muscle strength and endurance, phenotype and muscle fiber type-specific satellite cell content in frail elderly as compared to those elderly that do not classify as frail according to clinical criteria.
Verification of functional tests with the LoRRca, a next generation ektacytometer, on red blood cells of healthy individuals with or without comorbidities/risk factors.
To investigate FGF19 signalling and metabolic and functional consequences of a disturbed enterohepatic cycle in patients with obstructive cholestasis
Primary Objectives:1. To compare protein synthesis rate of the tumour and normal pancreas between cachectic and non-cachectic patients with pancreatic cancer.Secondary Objective(s):1. To compare protein synthesis rate of liver, intestinal, adipose…
The primary objective is to gain insight into the causative mechanisms of exertional dyspnea in HFPEF. We hypothesize that exercise induced pulmonary hypertension plays a significant role in the development of complaints. The secondary objectives…
Primary Objective: *To study differences in pulmonary function (i.e. increased airway resistance) one year after hospitalisation for RSV LRTD between mechanically ventilated and non-ventilated infantsSecondary Objectives: *To study…
The aim of this study is to explore the prevalence of HAND in people living with HIV.
First, to determine the extent to which microcirculatory perfusion defects occur during clinical kidney transplantation. Second, to study the relationship between these events and kidney function, inflammation and renal cellular injury. Third, to…
The current study aims to fill some of this gap by comparing family functioning in young people with MUPS to family functioning in young people with medically explained physical complaints and healthy young adolescents. Other family factors that are…
Our aim of the study is to investigate IL-7, TSLP and CD30(L) expression in SLE patients en healthy controls to better understand pathogenesis and to find a biomarker that is related to disease activity. With this potential new therapeutic targets…
To determine the choline levels of FNH, HCA and HCC using proton Magnetic Resonance Spectroscopy (expressed as parts per million).
The aim of the study is to gain more insight in the physiological mechanisms that are involved in child abuse.
1) Identify and further explore the structural and functional brain alterations in ALS patients, PSMA patients annd PLS patients in comparison to healthy controls and ALS mimic sydromes, both cross-sectional and longitudinal; 2) Explore anatomical…
1. Quantify changes in structural and functional brain networks within dyslexic readers, induced by an intervention with known and established behavioural effects.2. Examine whether short brain activity acquisition (5-8 minutes) of the resting state…
Goal of this study is to research family factors in case of adolescents with MUPS (N=64) and in case of adolescents with medically unexplained physical complaints (N=64). The following family factors are studied: family functioning (for example,…
Primary Objective: The primary goal of this study is to obtain BM and PB from healthy controls without overt cardiovascular diseases (ie patients that undergo orthopaedic or vascular surgery [atherosclerotic disease excluded]) in order to compare…
The purpose of the current study is to evaluate the difference in TICE in FHBL-patients as compared to unaffected controls, according to the previously developed stable isotope method with minor modifications (METC 10/092). This way we can prove the…
The aim of the study is to explore the prevalence of HAND in people living with hiv.
To clarify the aetiology of CTS and prognostic factors for the development of CTS.