1644 results
To test the hypothesis that vedolizumab has chemopreventive properties with regard to colorectal neoplasia in the high-risk group of patients with PSC/IBD.
Main objective is to identify ion-channel dysfunction in motor nerve cells of individual ALS patients, that contributes to their death, by assessing the association between ion-channel function tests in lower motor neurons and survival of patients…
To provide an extensive clinical and psychosocial characterization of IBS patients with and without psychological and/or physical comorbidities, as well as of disease-controls without IBS, but with psychological and/or physical disease, and a…
What are the differences and similarities of dopamine synthesis capacity between patients with AVH and BPD, those with schizophrenia, and healthy controls?
Despite seeing an increase in children admitted to the paediatric intensive care unit for severe acute asthma, we still do not know what the cause of this increase is, and we still only have few drugs we can give these children, regardless of the…
The purpose of UCC-SMART is to create multidisciplinary care of patients with cardiovascular disease and to create at the same time, by building a vascular cohort, a scientific infrastructure. The main questions of UCC-SMART are:* What is the risk…
The aim of this pilot study is to explore the structure and function of brain regions associated with the pain matrix in Breast Implant Illness (BII). This pilot study will be the foundation for grant application for future research.
- To compare the course and determinants of the SARS-CoV-2-specific humoral and cellular immune response in AID patients upon primary SARS-CoV-2 infection to that in healthy controls (HC)- To determine the seroconversion rate, magnitude and…
The primary goal of this study is to identify immunological alterations in lymphoid tissue of patients with various forms of inflammatory arthritis and systemic inflammatory diseases, and to correlate these alterations with diagnosis, disease stage…
The objective of this study is to investigate body image disturbances in adolescents with anorexia nervosa. To capture the multidimensional perspective, body image disturbances will be studied on a perceptual, cognitive-affective and a behavioural…
Identifying the pro-inflammatory biomarker profile in the pathophysiology of acute sever lung disease in SARS-CoV-2 infection, and using this profile to identify the patients who are at risk of developing acute severe lung disease and multi-organ…
The primary goal of this study is to identify the presence and possible pathogenic role of auto-antibodies in scleritis patients. Secondary goals are to evaluate the presence and role of matrix metalloproteinases (MMPs) in scleritis and its…
To compare salt taste and saliva characteristics in healthy volunteers and patients with CKD.
The two primary objectives of this study are: 1. To increase therapeutic effectiveness of an EMDR treatment session in PTSD patients by reactivating the updated traumatic memory during post-treatment sleep using TMR; and 2. To provide a neural base…
The first aim of this research is to identify predictors of one-year treatment response after initial clinical diagnosis in a large sample of adolescent girls with AN. The results of this study could allow us to assess different treatment strategies…
The overall objective of this study is to combine a conceptual model with empirical evidence to demonstrate that the start of a migraine attack corresponds to a critical transition that occurs when the dynamical brain system approaches a tipping…
The main objective of this study is to obtain valuable biomarkers that are useful in the prediction of the presence of (subtypes of PH) and/or treatment responses. Nucleic acid expression patterns will be determined in plasma and peripheral blood.…
Assess BMP10 secretion in patients with pulmonary arterial hypertension and its effect on right ventricular adaptation to pressure overload.
Project aims1. To provide a more precise overview of prevalence, presenting symptoms, referral routes, clinical complications and evolution during follow-up of PIDs in The Netherlands by registration and analysis of prospective patient data derived…
Main objectives are to identify brain areas involved in sensation of bladder filling through fMRI during urodynamic measurements. Secondary goals are to assess the correlation between bladder filling and subjects* bladder sensations in combination…