35 results
Objective: The primary goal of the current study is to study the immunogenicity and safety of HPV vaccination in patients with an autoimmune disease. Based on retrospective analysis with other vaccines we hypothesize that patients with autoimmune…
To develop non-invasive markers for tissue changes in skeletal muscle using MR methods
The primary objective of the study is to assess the effect of missed doses of atomoxetine and OROS methylphenidate in ADHD patients who are stable on pharmacotherapy based on the patient*s daily behavior as assessed by the Daily Parent Report of…
1. Is there a difference between the level of activities and participation among adolescents with chronic musculoskeletal pain as compared with the activity and participation level of adolescents not suffering from chronic pain?2. What is the impact…
Aim of this study is to acquire more insight in the relation between risk factors for cardiovascular disease and type 2 diabetes and anthropometric measures such as BMI, waist circumference and body fat percentage and compare the results between the…
The objectives of this pilot study are to explore differences in sleep and fatigue, and the relation with the function of the HPA axis, between survivors of childhood ALL and healthy controls.
This research proposal focuses on (i) the development and implementation of experimental approaches to identify dimensions of impulsivity, empathy and paranoia. (ii) Studying the gene-environmentinteractions which are expected to play a role in the…
The main objectives of the present study are: determining short and long term effects of TF-CBT and EMDR; assessing the efficiency of these therapies; and identifying the characteristics of those children who do not respond to the given treatment.
To describe the prevalence of enteropathogenic viruses in children with primary (CVID and CVID-like disease) and secundary immunodeficiencies and a potential relation between this prevalence and the development of auto-/allo-immune enteropathy.
The objective of this study is threefold. The first objective of the study is to determine the course of pervasive developmental disorders (more specific PDD-NOS) and thought problems (more specific MCDD). Secondly, possible processes underlying…
Using state-of-the-art MR methods, this project aims to acquire a detailed understanding of the biochemical, structural and genetic background of the cognitive impairment in DMD and to determine whether the previously found differences between…
To evaluate if the program *Run2gether* can change physical behavior in children with obesity and/or diabetes, and thereby increase physical fitness level and insulin sensitivity en reduce body weight. An additional goal for children with diabetes,…
To sess the relationship between cerebral perfusion and clinical findings (neurological and neuropsychological) in patients with sickle cell disease.To compare iamging fincdings in children with and without sickle cell disease.
To investigate the relation between a known genetic variation in a set of selected genes involved in the recognition of microorganisms and inflammation and the frequency of respiratory tract infections in a group of children with DS.
Routine evaluation of dyssynchrony in pediatric patients with cardiac disease is feasible using standard and novel echocardiographic techniques. The extent of cardiac dyssynchrony and its influence on cardiac function differs between groups of…
To test the surgical feasibility of the less invasive percutaneous pedicle screw instrumentation system for the treatment of children with a so called "hypotonic" scoliosis. Additionally, postoperative pain reduction and a reduced hospital…
1. To assess the long-term outcomes of the PATHS intervention in terms of symptoms of behavioral and emotional problems at ages 9, 10, 11, 12 years, and in terms of number of DSM-IV clinical diagnoses (age 12 years), cases of school failure (…
The first objective is to determine the effects of neonatal GC treatment on basal behavioral and neuropsychological measures, emotion and motor development during adolescence. The second objective is to study basal physiological parameters in ex-…
First, to develop a diagnostic method for non-infectious uveitis in childhood. Second, to analyze iris and ciliary body tissues of children with uveitis on the presents of inflammatory infiltrate. The results of this study will contribute in the…
To support future scientific research into late effects of treatment for childhood cancer