114 results
Spinal anesthesia induces several alterations in normal brain processes. Firstly, loss of afferent information increases pain sensitivity. In our previous study on the effects of spinal anesthesia (P11.221) we showed that subjects felt more pain…
The primary goal of this research project is to evaluate the implementation of VR to PCIT. We expect to find that PCIT-VR will ameliorate positive parenting skills, leading to faster skill mastery. We believe that if the positive parenting skills…
The hypothesis is that a combination of exercise therapy and splinting is superior to splinting alone in the treatment of patients with thumb base osteoarthritis.
We hypothesize that there is no difference in survival, clinical and radiological follow-up after >12 years of follow-up between the scarf and chevron osteotomy.
Physcial therapy is an effective treatment for patients with hip impingement
B cells play a role in multiple sclerosis, not only by production of autoantibodies but also by presentation of (auto)antigens to autoreactive T cells.
Children born small for gestational age (SGA) might be at increased risk for developing hypertension, cardiovascular disease and diabetes mellitus type 2. It has been shown that those SGA children with relatively higher GH levels during an overnight…
1.The Dutch version of the walking impairment questionnaire is a valid instrument for measuring walking disability in patients with peripheral arterial disease; 2.There is a difference between the walking ability experienced by patients on a…
We hypothesize that we are able to develop a flow-cytometric assay that is able to detect rabies-specific B-cells in the blood of hyperimmunized people.
(1) patient self-monitoring is not inferior to standard of care in terms of DAS 28 score; (2) patient self-monitoring in RA patients will reduce outpatient clinic visits, and will consequently decrease healthcare costs.
We hypothesize that the subpopulation of CD68+Tie2+ macrophages is increased in diabetic patients in comparison to non-diabetic individuals. These macrophages may cause an increased expression of Ang2 in plaques, thereby enhancing angiogenesis which…
We hypothesize that the ddPCR has a sensitivity of at least 80%
In a randomised, single-blinded, open trial, patients with GTS or CTD will be randomized for medical treatment (Risperidone) or behaviour treatment (exposure and response prevention, ERP). Risperidone has been shown effective in tic disorders, as…
1) Left bundle branch area pacing is superior over right ventricular (RV) pacing. 2) Acute electrical and hem-dynamic effect is comparable between LV septal pacing and left bundle branch pacing.
PVAT plays an important role in driving vascular ageing manifested by medial smooth muscle cell (SMC) dedifferentiation into an osteogenic phenotype that induces intimal and/or medial calcification. I furthermore hypothesize that this process of…
Cardiorespiratory fitness (CRF) is expected to be lower in COVID survivors on short and long term compared with applicable reference values and is expected to remain low on the long term in a considerable subset of patients. CRF measured with a…
Use of CPR as indicator for delivery in reduced fetal movements reduces perinatal mortality and improves neonatal outcome and long-term outcome.
We expect the “movement with pain” program will result in a reduction in disability, improved perceived recovery, improvement of psychological wellbeing and increase in physical condition. Moreover, we expect that a combination of the amount of…
While head and neck surgeons aim for a 1 cm healthy tissue margin during resection of OSCC, pathological examination often reveals a smaller margin. Our hypothesis is that this occurs due to shrinkage of mucosa following the resection and due to the…
Improved detection of tumor.