33 results
Systematic gathering of biomaterial and phenotypic data of IBD patients during clinical care provides assessment of molecular markers in the DNA, the transcriptome and proteome. The markers can be associated with the different disease phenotypes…
This intervention study investigates the effectiveness, costs and cost-effectiveness of a protein-enriched diet and resistance exercise training for 3 months on bone and muscle health, and quality of life in older adults recovering from an acute…
1) To determine if the 24 hour admission with TM can be omitted safely in the setting of CER for patients with low- and intermediate risk syncope (non-inferiority) 2) to determine the health care cost reduction (superiority), 3) additional…
To investigate the feasibility of increasing preoperative dietary fiber intake in CRC patients undergoing surgery via 1) personalized dietary advice (Vezel-UP tool), or 2) vegetable product containing natural fibers (WholeFiber) compared to 3)…
The primary objective is to compare a composite endpoint of major CV events and all-cause death between control and intervention group.Secondary objectives are the comparison of patient-centered outcomes between the two groups.
Primary Objective:- To compare adenoma detection rate (ADR) with versus without real-time automated detection (CAD EYE, Fujifilm)Secondary Objectives:- To compare the size, morphology and histology of adenomas detected and resected in both arms of…
The LIMONCELLO study aims to assess the effect and cost-effectiveness of TMPC compared to usual care.
To investigate the role of the immune system in the etiology and prognosis in an acute ischemic stroke (or TIA) in young stroke patients.
The primary objective of the proposed research is to investigate in patients with PDD the efficacy of STN-DBS with best oral medical treatment (DBS-group) for disabling motor symptoms during off-drug phase compared to best oral medical treatment…
The primary objective of the PROTECT IV Trial is to demonstrate the superiority of percutaneous coronary intervention (PCI) performed with Impella® mechanical circulatory support (MCS; Impella CP®, Impella CP® with SmartAssist® or Impella 2.5®…
To assess the effectiveness of a cerclage in women with a twin pregnancy with a midpregnancy short cervix compared to standard treatment (no cerclage) in the prevention of extreme preterm birth (PTB) < 28 weeks of GA.
To evaluate in SSc patients with low risk for disease progression 1) whether assessment in an outpatient clinic setting is an acceptable alternative for evaluation in the Care Pathway. Outcome parameters we will evaluate include 1) health care…
Primary objective1. The primary aim of the study is to answer the question whether specification of a positive direct antiglobulin test and/or red blood cell autoantibody specification is correlated with the clinical course in patients with AIHA.…
The objective of the study is to explore potential beneficial effects of improvisation-based musical training: 1) on speech-on-speech perception and music appreciation in CI users, 2) on HR-QoL-related aspects as well as to explore other nuances in…
The objective of this study is to deep phenotype CIndU (subtype SD and ColdU) and detect novel biomarkers for diagnosis and treatment response as well as establish methodologies for (non-) invasive monitoring of treatment effects in chronic…
Primary Objective The primary objective of this study is to compare the 3-year overall survival of stage III NSCLC patients during follow-up surveillance with 18F FDG PET/CT versus follow-up with conventional CT surveillance. Secondary…
Primary:1. Do twelve weeks of MegaPower training effectively accomplish patient-tailored participation and activity goals in ambulant children with CP, when compared to their usual care? Secondary:1. Do twelve weeks of MegaPower training improve…
The aim of the EXACT@Home study is to further improve the assessment of treatable traits in patients with difficult to treat to severe asthma using ehealth before considering treatment with biologics.
To assess the effect of adding a tapering decision aid on a dynamic flare prediction model to disease-activity-guided dose optimisation (DGDO) on the incidence of flares and medication use.
The aim of this study is to identify whether it is possible to safely discontinue treatment in stable RRMS patients who have shown no evidence of active inflammation in the years prior to inclusion in terms of the return of inflammatory disease…