141 results
The aim of the study is to compare the outcome of two DES with biodegradable polymer coatings separately (Orsiro and Synergy) versus an established third-generation durable polymer DES with proven efficacy and safety (Resolute Integrity) in an all…
The objective of the REPRISE III trial is to evaluate the safety and effectiveness of the Lotus* Valve System for transcatheter aortic valve replacement (TAVR) in symptomatic subjects with calcific, severe native aortic stenosis who are considered…
A lower hemoglobin concentration for red cell transfusion (restrictive transfusion strategy) will be non-inferior to a liberal strategy in terms of vital organ function (heart, brain and kidney) and mortality.
1. To get new insights in the pathophysiology of PPS by comparing tissue characteristics (histology) of the pericardium in patients with and without PPS. 2. To identify biomarkers that are associated with PPS by collecting 4 blood- and 1 pericardial…
The primary objective is to investigate the determinants of aortic root deformation occurring >= 3 months after successful ASO implantation in adult patients with an atrial septal defect.
To study patients with severe HF who would benefit from off-pump SVR using the Revivent Myocardial Anchoring System. To investigate the characteristics of the ischaemic heart using CMR or cardiac CT in order to verify patient eligibility for the…
The primary objective of the study is to determine whether the intrinsic electrical delay (QLVs) at a specific pacing site is correlated to acute hemodynamic response (by percentage increase in strokework, %SW) in CRT with a quadripolar lead.
To evaluate the safety and performance of the Lotus Valve system for transcathether aortic valve replacment (TAVR) in symptomatic subjects with severe calcific aortic stenosis who are considered high risk for surgical valve replacement.
Ex vivo study: What is the relation between increasing heparin concentrations and different protamine:heparin-ratio*s with POC-PT values in blood drawn from healthy volunteers?Clinical study in cardiac surgery: Does the POC-PT device correspond with…
Bloodloss study after Aortic valve replacement
Impact of Mecc perfusion vs conventional ECCperfusion
Peri-operative Bloodloss after Aortic valve replacement
To investigate whether high resolution multi-site epicardial mapping of the atria in patients with structural heart disease undergoing cardiac surgery can identify patients at risk for developing early post-operative atrial fibrillation. The…
These clinical pilot study examines whether there are differences between patients with ejection fraction (LVEF) > 30% who have undergone a CCABG or OPBH. We look at te myocardial damage, the use of inotropica, blood loss and blood…
- To determine the effects of the pacing site on prevention of AF episodes - To examine the relation between the pacing site, reduction of AF episodes, quality of life, heart failure, number of cardioversions, frequency and duration of hospital…
Primary research questions To investigate whether the outcome after the randomized implantation of the Resolute Integrity® versus Promus Element® drug-eluting stent are similar, as assessed in a non-inferiority setting by comparing target-vessel…
To compare the effectiveness of PVI and VATS-PVI. Secondary objectives are to compare the duration of hospitalisation, quality of Life, cost and to compare the satisfaction of the patients.
To assess if serial hybrid ablation for freedom of AF is superior to epicardial ablation alone in patients with (long-standing) persistent AF
The aim of our study is to evaluate clinical outcomes of patients primarily closed over Redon catheters for the treatment of PSM, comparing the application of local gentamicin with a control group.
The primary objective is to demonstrate the safety and feasibility of the STENTYS-BDS.
The main objective is to determine the early and late survival and reoperation outcome of VSARR in patients suffering from aortic root aneurysm with or without aortic regurgitation. Furthermore, we will evaluate the quality of using a SF-36 form.…
Conduct a multicenter randomized clinical trial to assess whether the use of the decision aid results in optimization of shared-decision making and improved quality of life in patients who have been accepted for aortic and/or mitral valve…