14 results
to investigate the course of the pancreatic enzymes (serum amylase, serum lipase and urinary amylase) related to the course and stage of acute pancreatitis and thereby calculating the diagnostic accuracy of each pancreatic enzyme for acute…
Primary objectives:to describe the composition of intestinal microbiota in the course of pediatric IBD-patients by IS-proto describe the composition of intestinal microbiota of apparently healthy children, aged 4-17 years, by IS-pro Secondary…
The overall objective of this study is an improvement in (early) diagnosis of NEC and its life-threatening complications, thus to be able to detect children who are *at risk* for NEC and its complications as early as possible. To this end we will as…
To evaluate the presence of anatomical changes in painful joints in IBD patients with a dedicated peripheral extremity MR scanner.
Assesment of small bowel CD activity using the NBI compared to the conventional white light endoscopy, using the single balloon enteroscopy system in patients with known CD and suspected small bowel disease activity.
Primary objectiveTo define a parameter, or parameters, in peritoneal drain fluid that have diagnostic value for clinically manifest anastomotic leakage of a colorectal anastomosis in the early postoperative period.Secondary objectivesTo compare the…
The objective is to investigate the correlation between bacterial/viral gut infections and acute appendicitis in children.
The aim of the project is to validate biomarkers for the development of a peripheral blood test which can distinguish early inflammation between various forms of IBD, with the use of novel techniques, such as mass cytometry and RNAseq.
The main objective of this study is to investigate the migratory behaviour of neutrophils isolated from healthy individuals and gluten-related disease patients* blood to develop a diagnostic tool for gluten-related diseases that can replace biopsy…
Develop cellular blood tests applicable in routine specialized diagnostic settings for CD in patients on a GFD and patients with idiopathic villous atrophy and atypical presentation of CD. **
1. Comprehensive phenotypic analysis and comparison of mucosal immune compartment in patients and controls ex vivo (year 1-3);2. Comprehensive phenotypic analysis and comparison of mucosal stromal cell compartment in patients and controls ex vivo (…
Assessment of the detection of neoplastic lesions in patients with longstanding inflammatory bowel disease, using different endoscopic imaging techniques. Colonoscopy will be performed with either A) HDWLE, B) back-to-back HDWLE or C) CE.
The main objective of this study is to evaluate whether earlier establishment of Critical View of Safety can be obtained during laparoscopic cholecystectomy, by applying NIRF laparoscopic imaging as an adjunct to conventional laparoscopic imaging…
In this study, we are looking at the effectiveness of following phase 3, the maintenance phase, of the Crohn's Disease Exclusion Diet (CDED) compared to normal diet (with or without standard maintenance treatment) in children and adults with…