23 results
The main objective of this study is to assess more thoroughly the differences in gait patterns between COPD patients and healthy controls. Other objectives are to assess differences in gait patterns between GOLD stages and two age groups in healthy…
Research questions: Primary questions:* Are the new point-of-care instruments for the measurement of VOCs in exhaled breath feasible for use in children and adolescents aged 6 to 20 years?* Are these techniques able to differentiate between healthy…
The first aim of this study is to determine the prevalence of cognitive impairment in COPD patients compared with persons without COPD and to compare cognitive functioning between patients referred by their general practitioner, patients referred by…
The first aim of this study is to determine the prevalence of cognitive impairment in COPD patients compared with persons without COPD. The second aim is to study the clinical characteristics of COPD patients with cognitive impairment. The third aim…
This study aims to determine whether the ILC populations differ in the lungs of different phenotypes of asthmatic patients and healthy subjects and how these cells are regulated by bronchial epithelial cells. Furthermore we want to study how this is…
In the present study we want to examine the effect of salbutamol on the muscle tone of the diaphragm. We also want to examine the correlation between muscle tension measured by EMG and the Clinical Asthma Score. To include the children that come to…
Primary objective:Test whether preservation of upper limb compared to lower limb muscle function is associated with preservation of functional arm use compared to functional leg use in daily life in patients with COPD compared to healthy controls.…
Quantify how many frail elderly aged over 65 years with reduced exercise tolerance and/or exercise induced dyspnoea have previously unrecognised COPD and heart failure.Quantify the difference in prevalence of unrecognised COPD and heart failure…
The aims of our study are:1. To use electronic nose measurements to discriminate between well-defined groups of children with different levels of asthma control. 2. To use electronic nose measurements to distinguish between different levels of FeNO…
Research questions:1. Is web-based monthly monitoring using the Asthma Control Test (ACT) cost-effective?2. Is asthma management guided by the fraction of nitric oxide in exhaled air (FENO) cost-effective?We hypothesize that both strategies are…
To determine exercised-induced bronchoconstriction with an objective and standardized exercise test for infants and young children (3-6 years); to compare resistance and compliance in wheezy children and healthy children before and after exercise-…
Primary objective:Study A: Development, validation and reproducibility of a method to assess arm activity.Study B: Investigate the association between muscle effort and arm use during a series of daily activities in COPD patients and healthy age…
The aim of the study is to improve the clinical care and QoL for patients with COPD. We want to do this by means of the evaluation of the efficacy of pulmonary rehabilitation on cognitive function, mood, anxiety, and QoL in people with COPD. In…
Study 1.Primary Objective: To investigate whether a portable electronic nose system (Cyranose 320) can discriminate the smell-prints before and (several time points) after the smoking of 1 cigaretteSecondary Objective(s): Is the effect the same for…
1. To test feasibility of mannitol inhalations in a Dutch pulmonary out-patient clinic.2. To compare time and costs involved in measuring airways hyperresponsiveness by methacholine to mannitol
1. To test feasibility of mannitol inhalations in a Dutch pulmonary out-patient clinic.2. To compare time and costs involved in measuring airways hyperresponsiveness by methacholine to mannitol
To investigate the association between AGE, COPD severity and number of packyears.
The objective is to find the most effective combination of wearable devices to accurately reflect paediatric asthma control in a home monitoring situation, by studying the relation of the home-measured signals to the currently used exercise…
- To assess the feasibility of a study protocol to determine acute effects of short-term roadside traffic exposure (i.e. BC) in patients with COPD. - To collect preliminary data that provide insight in acute effects of short-term roadside traffic…
The objective of the study is to determine whether the new PTR-QiTOF method can successfully differentiate between seniors without specific health complaints and those who suffer from diabetes mellitus type 2, asthma, or irritable bowel syndrom.…