42 results
Previous studies have shown that the half life of adalimumab increases to up to 21 days, after several doses have been administered. As such it seems possible to increase the dosing interval from 14 days to 21 days, in patients IBD in long term…
Playing a EMG controlled video game that simulates relevant aspects of ADL prosthesis use, will lead to improved performance of a prosthesis task in comparison to controls.
Our primary outcome is to change knowledge, attitude and managing skills of prison staff. We hypothesis that the elearning module will contribute to improve knowledge, attitude and skills
The use of a clinical decision support system will increase adherence to the ESC guideline for atrial fibrillation in terms of calculation of CHA2DS2-VASc score and HAS-BLED score, and the resulting accurate antithrombotic treatment.
The main aim of this project is to conduct a randomized controlled trail (RCT) to evaluate the effectiveness of the videogame Dojo as an intervention for anxious-aggressive youths in residential treatment. The effectiveness of Dojo will be compared…
We hypothesize this difference is due to differences in the mechanisms by which the individuals can withstand and/or adapt to the stress conditions applied in the clinical model and that these mechanisms are of key importance in our ability to…
The hypothesis of this study is that dosing everolimus 5mg twice daily(BID) instead of 10 mg once daily (QD) decreases the incidence of side effects, as a result of a lower Cmax while maintaining Cmin and AUC.
The Versascope (3.5-5.3mm diameter) induces less pain than a conventional hysteroscope (5.5mm diameter) during a hysteroscopic procedure in an office setting.
Welke techniek voor het sluiten van de wond na excisie van een sinus pilonidalis leidt het snelst tot volledige wondgenezing. Onderzocht worden het primair sluiten in de midline en de Limberg-plastiek.
Public health nurses who are trained in providing oral health advices and in inpecting the mouth reduce the prevalence of ECC more than nurses that are not trained.
The effectiveness of a school-based immersive video game (Dojo) in preventing anxiety will be tested in a Dutch sample of adolescents with elevated anxiety symptoms. It is expected that the adolescents who receive the intervention video game will…
In this randomized study, reduction of incidence and intensity of postlaparoscopic pain will be estimated by using a combination of two therapies, intraperitoneal normal saline and the pulmonary recruitment maneuver.
The effect of EMDR in adults with autism has not been studied before. Hypothesis is that the severity of traumarelated symptoms decreases after treatment with 8 sessions EMDR in comparison of treatment as usual. There are indications of diagnostic…
The hypothesis is that modarate and late preterm infants at age 12 reported more symptoms consistent with asthma and use more asthma medications, as well as a poorer lung function, exercise capacity and Lung Clearance Index than healthy peers.
The effectiveness of the commercial video game Journey in preventing depression will be tested in a Dutch sample of adolescents with elevated depressive symptoms. In an RCT design the effectiveness of Journey will be compared to the effectiveness to…
Patients treated with MIS will document lower back pain scores on VAS at the short-term follow-up (first 6 weeks after surgery) as compared to open surgery.
The widespread use of antipsychotic polypharmacy may reflect some rationale of polypharmacy despite the lack of evidence to support this. For some patients polypharmacy may be a better option than guideline recommended monotherapy. In view of…
1) Implementing TIPP will prevent acute emergency room (ER) visits, rehospitalisations and inappropriate referrals 2) Implementing TIPP improves transitional patient safety culture 3) Although TIPP aims at reducing transitional incidents,…
This study will investigate the effects of a fluid challenge on microcirculatory vessel perfusion and the glycocalyx thickness. It is hypothesized that infusion of crystalloid fluids in healthy subjects is associated with a volume-dependant…
•Participants in the experimental (i.e., mindfulness exercises) and control (i.e., emotion registration) condition will experience a decrease in prolonged cardiovascular activity, indicated by a increase in heart rate variability and an decrease in…