67 results
To evaluate the efficacy of various masking strategies in cochlear implants as a treatment for tinnitus in patients with profound hearing loss.
to measure neural activity of the central nervous system in tinnitus related brain areas in cochlear implant recipients with chronic tinnitus and to determine the relation between this neural activity and the subjective tinnitus experience of…
The aim of the present study is to investigate cerebral vasoreactivity in response to lower body negative pressure in young and elderly healthy men, as a measure of cerebral autoregulatory responsiveness.
To determine the feasibility and the estimation of the effect for the primary study parameter of a cognitive rehabilitation treatment for deficits in social cognition after traumatic brain injury.
Translation follows at a later stage.
Does anesthesia itself or transition of anesthesia to an awake state and vice versa lead to changes in the lactate/pyruvate ratio, glucose, glycerol and glutamate concentration as measured in the brain interstitial fluid?Are the metabolic…
The primary objective is to evaluate the presence of brain damage (defined by white matter lesions (WMLs) or cerebral atrophy or deviations at neuropsychological examination (NPE)) among adults with tetralogy of Fallot (TOF). The secondary objective…
The present study will examine how young-onset-dementia patients and their families can be supported in their home environment as long as possible and institutionalisation can be delayed. For this the functioning and care needs of young-onset-…
The most important objective of this study is the validation of various examination procedure to assess fitness to drive in older persons with cognitive impairments. The assessment procedure comprises nosological dementia diagnoses (e.g. AD, FTD) ,…
Primary objective: To determine whether the short-term neurological outcome of surviving children diagnosed with prenatally diagnosed ventriculomegaly is associated with the extent of VM before birth.Second objective: To determine whether the…
To assess the impact of OH on cerebral perfusion and function in severe OH in AF (n=10) and healthy controls (n=10).
To evaluate whether GH substitution in patients with an isolated GHD after TBI could reverse the severity of symptoms which characterize GHD.
Primary Objective: In this study, we will investigate the feasibility of a newly developed methodology for diagnosing the visuoperceptual hemifield abilities of young children with early damage to the visual system. Secondary Objective(s): Secondary…
The eventual aim of the study is to determine the effects of Botulinum toxin injections in the bladder on overactive bladder. The objective of this initial study is to determine what brainstructures are activated in respond to increasing volumes of…
The main objective of this study is to characterize the flow of information in the fronto-parietal network during the simulation of movements using intracranial EEG recordings. In the characterization we will pinpoint the neuronal (sub)regions of…
To determine the relative bioavailability of pramipexole 4.5 mg tablets vs. 4.5 mg Sifrol in healthy subjects after up-titration.
The general objective is to validate and assess the clinical and economic added-value of a) innovative diagnostic tests developed in WP1 (PET tracers), WP2 (ultra high field MRI) and WP3 (CSF), and b) other emerging diagnostic tests for Alzheimer…
The first (primary) objective (study 1) is to examine 1a) risk factors for volume loss in the entorhinal cortex and compare these with risk factors for volume loss in the rest of the hippocampus at 1.5T MRI over 7 years of follow-up; and to examine…
To determine whether CT optimal touch reduces pain experience in PD patients.
Understand perceptions of people with young-onset dementia and their family caregivers about quality of life, advance care planning and care including end-of-life care, and understand what professional caregivers can learn from understanding and…