489 results
This study aims to gain clarity on the issue of treatment for clinical levels of social anxiety in adolescents by testing the effectiveness of a group-based intervention. Most importantly, it aims to research the effectiveness of an added mHealth…
Primary objective To evaluate the Overall Response Rate (CR/PRrate) in patients treated with pembrolizumab for recurrent or progressive PCNSL after MTX-based first-line therapy To evaluate the safety of pembrolizumab in subjects diagnosed with…
Primary Objective: Non- invasive determination of the oxygenation values and the haemoglobin concentration of retinal arteries and veins by means of retinal imaging.
Safety:* Evaluate the safety of AVXS-101 through incidence of adverse events (AEs) and/or serious adverse events (SAEs)* Evaluate the safety of AVXS-101 based on the change from baseline in clinical laboratory parametersEfficacy objectives will be…
This is an exploratory validation study in a small group of subjects receiving a CI to verify if ECoG measurements with AB*s novel ECoG system are useful as an intra-operative tool for soft surgical techniques to spare residual hearing. This trial…
Thermoregulation in patients with spinal cord injury and cold sensations, an explorative pilot-study
To investigate whether SCI patients with regular complaints of cold sensations in daily life have more impaired thermoregulatory responses to changes in environmental temperature compared to SCI patients who do not have these cold sensations in…
Evaluate whether CT lung densitometry and PWV associate with plasma DES concentrations. In addition, we want to determine whether certain other laboratory determinations in the blood and condensed exhalation vapor correlate with plasma DES.
The primary objective of this study is to investigate if shear-wave elastography and contrast-enhanced ultrasonography can identify those patients most suitable fir an intervention (surgery or endoscopic balloon dilation) and those patients that…
The collection of data of the orofacial motor skills with the OMOK in healthy children between 2 and 8 years.
Taken together, social performance monitoring processes and empathic abilities are key ingredients for efficient social behavior. Possible disturbances in these processes may severely inhibit or even impair social interactions with possible long-…
To determine the efficacy of a filter-based depletion of RBC-pathogen complexes by a single apheresis tretatment in patients with sepsis.
The primary objective of this study is to evaluate the safety and feasibility of 3 months martial arts based training program for DMD patients. The secondary objective is to gain a first impression on the program*s ability to optimally use one*s…
The primary objective of this study is to describe the long-term safety of dupilumab in the treatment of patients with moderate to severe asthma who completed the previous asthma clinical trial, TRAVERSE-LTS12551.
To compare the immunobiology of healthy volunteers to (advanced) cancer patients to age-matched controls with no history of cancer and no potentially interfering medication.
Investigate anatomy, kinematics, clinical outcomes, and functional outcomes in Madelung deformity patients.In this study we will answer the following 3 questions:1) What is the anatomical situation of the wrist in patients with Madelung deformity,…
To assess the feasibility of real-time MRI temperature monitoring and ablation zone assessment during thermal ablation of liver tumours.
To establish the point prevalence rate as well as the lifetime prevalence rate of sexual hallucinations in patients diagnosed with a bordeline personality disorder, and to establish the relation of these hallucinations with childhood trauma as well…
The aim of this study is to investigate the amount of clinically relevant SRML (defined in this study as *5% muscle loss within one week measured by the cross sectional area (CSA) of the different muscles) in patients after major abdominal surgery…
The objective of this study is to investigate the feasibility of treating breast and lung cancerpatients in mDIBH using nasal a high-flow therapy (NHFT) device.
- To study the success rate of organoid culture from lymph node, visceral and bone metastases in metastasized urogenital cancer and examine which parameters influence the success rate (culture media, biopsy site, cell counts). - To study the…