425 results
To determine whether micellar curcumin is able to restore functional lymphocytes in pancreatic cancer patients with stable disease after standard of care treatment.
The primary objective of this study is to determine the feasibility of intraoperative fluorescence imaging detection of PitNET tissue during TSS using the VEGF-targeting optical agent bevacizumab-800CW in tumors with a Knosp grade of 3 or 4.…
10 years ago we selected an unique cohort of 154 patients with acute ACL injuries, who were prospectively characterized over the first two years post-injury. A single follow-up measure within this established cohort is proposed, to those that gave…
The primary objective of this study is to investigate the quality and content of the MTT-EP model in response to electrocutaneous stimuli by determining stimulus-related and/or physiological-related components, before and after the occurrence of HFS…
Primary Objective: To assess the agreement between the heart rate assessed with a dedicated cap with integrated PPG-leads and standard ECG monitoring using regular neonatal thoracic electrodes as reference technique.Secondary objectives:Does…
(I) To compare patient friendliness in adult psoriasis patients between two non-invasive cytokine detection methods: TAP and TAPE. (II) To assess the correlation in cytokine detection by TAP and TAPE stratum corneum sampling in psoriasis patients.
This pilot does not aim to demonstrate the effectiveness of the system. The effectiveness of the system has been demonstrated in the recently published study: Chromed study, a multi-center Randomized Controlled Study.This pilot aims to obtain…
To assess T cell activation in patients with extremely high Lp(a) levels versus controls with low Lp(a)
This study has a strong explorative and qualitative approach and set-up. Please note that the goal of the study is to further identify possible areas for innovation for professionals, patients and their partners. The aim for this study is NOT to…
The current study aims to assess the impact of self-quarantine on glycemic control. In addition, this study describes diabetes self-management, well-being and distress in Dutch patients with type 1 and type 2 diabetes, during a nationwide period of…
To evaluate the safety of BIVV001 in previously treated pediatric subjects with hemophilia A.
Although electroconvulsive therapy (ECT) is an effective treatment for depression, preventing relapse after successful ECT remains a major challenge. In the PRASED-study we evaluate the effectiveness of three strategies to reduce relapse: an…
The primary goal of this research project is to study physiological responses of typically developing (TD) children and children with CP (only if the results of TD children are promising) to discomfort induced by the use of technological devices…
Validate the presence and correlation of intraoperative modifiable risk factors for colorectal seam leaks.
To investigate if the GON-injection affects trigeminal threshold and transmission using the R2 component of the blink reflex.
To establish a point prevalence of asymptomatic proximal lower extremity DVT in patients admitted to the ward with COVID-19.
Objectives:Primary Objective: to investigate the anti-tumor efficacy of domatinostat in combination with avelumab in advanced unresectable/metastatic MCC patients progressing on anti-PD-(L)1 antibody monotherapy.Secondary Objectives: to investigate…
Primary objective:- To investigate if neo-adjuvant combination of talimogene laherparepvec and nivolumab will achieve a pathologic response rate of 45% complete responses (either *pathological complete response (pCR)* or *pathological near complete…
The primary objective of this study is to demonstrate that our DLA-based method is promising enough to detect CTCs in ER+, N+ primary breast cancer patients after 5 years ET. Simultaneously, other methods (CTC detection in 7.5 ml and 30 ml of blood…
The current study investigates which brain areas are related to habituation of pain (using fMRI) and enables a direct coupling with concurrent EEG. We will test the hypothesis that activation of areas in the brain show changes over time as correlate…