264 results
This study has been transitioned to CTIS with ID 2023-503312-32-00 check the CTIS register for the current data. Possibly, outcomes of treatment of irresectable squamous cell carcinoma of the esophagus can be improved by adding bintrafusp alfa to…
This study has been transitioned to CTIS with ID 2023-508832-68-00 check the CTIS register for the current data. Dose escalation: To establish the MTD and RP2D of tisotumab vedotin in combination in subjects with cervical cancer Dose expansion:…
To verify the uncemented Triathlon Tritanium Knee System safety during follow-up and survivorship as described by Kaplan-Meier survival curves.To document the patient clinical outcome of the patients who have received an uncemented knee arthroplasty…
This study has been transitioned to CTIS with ID 2023-506987-15-00 check the CTIS register for the current data. 1) Objective: To evaluate the safety and tolerability of the pembrolizumab combination therapy.2) Objective: To estimate PSA response…
This study will investigate the potential value of CFX treatment, by prospective monitoring of functioning in patients that undergo this treatment. Likewise, aspects of the treatment that are important for patient experience will be systematically…
This study has been transitioned to CTIS with ID 2024-515964-30-00 check the CTIS register for the current data. • Allow patients to continue or start AP01 therapy for the treatment of ILD and IPF prior to regulatory approval or until the study is…
This study has been transitioned to CTIS with ID 2024-512007-39-00 check the CTIS register for the current data. Primary objectives: Part A: Generate an airway gene expression signature for itepekimab treatment using RNA sequencing in former smokers…
Predict response to FOLFIRINOX treatment in patients with LAPC based on baseline stiffness values derived with MRE.
The main goals of this study are to study the effects of VHPSD ablation on the duration of a pulmonary vein isolation procedure, and on transient (edema) and persistent (fibrosis) effects of VHPSD ablation in the left atrial wall.
The main objective of this study is to assess the effectiveness of an integrated program of fitting and training interventions aimed at reducing unexpected variability and addressing the specific error patterns of each recipient.
Primary aim: To establish reference values for exercise-induced elevations of cTn concentrations following walking, cycling and running exercise. Secondary aim: Assess the prevalence of (sub)clinical coronary artery disease in individuals with high…
Implement BBB-ASL at VUmc and assess the reliability and reproducibility of f measurements in healthy volunteers and patients with glioma
Objective: Evaluate uterine contraction features (frequency, amplitude, direction, and coordination) using a dedicated speckle-tracking algorithm by 2D transvaginal ultrasound measurement in postmenopausal women presenting with vaginal bleeding or…
Through the utilization of fMRI and DUS we aim to illustrate the physiological change a kidney graft undergoes during a transplantation trajectory from donor to recipient. Secondarily, we intend to establish a baseline reference for normal…
This study has been transitioned to CTIS with ID 2023-505067-36-00 check the CTIS register for the current data. Primary objective: To determine the safety and tolerability and to establish a preliminary recommended Phase 2 dose (RP2D) of MK-1484…
This study has been transitioned to CTIS with ID 2024-514168-15-00 check the CTIS register for the current data. Primary: To determine the maximum tolerated dose (MTD) of 1 or 2 cycli Lu-PSMA when given concurrent with EBRT+ADT. Secondary: To…
This study has been transitioned to CTIS with ID 2024-511966-36-00 check the CTIS register for the current data. To evaluate the bilateral SLN detection rate of intraoperative ICG with NIR fluorescence imaging compared to the current standard of…
1. To measure clinical outcome of patients with an autoimmune encephalitis longitudinally.2. To evaluate existing PROMS, developed for other (neurological) disease, for patients with an autoimmune encephalitis.3. To develop and validate disease-…
This study has been transitioned to CTIS with ID 2024-513622-35-00 check the CTIS register for the current data. The primary objective of this study is to assess the number of detected pheochromocytoma lesions, proved by histology, with [18F]mFBG…
Accuracy and usability of the navigation setup during rectal surgery.