22 results
The objective of the study is to obtain information on the bioavailability and pharmacokinetics of the phenolics present in an olive leaf extract (Bonolive®, dose 250 mg), standardized on 40% oleuropein, and to identify the composition of the…
1) to investigate cognitive functioning in lacunar infarct patients with and without periventricular white matter lesions; 2) to identify predictors for cognitive dysfunction in lacunar infarct patients.
The aim of this study is to elucidate the effects of RT on the oral microcirculation in patients with malignant disease in the head and neck region. We want to test the hypothesis that radiation therapy triggers microcirculatory derangements which…
To assess structural changes in the radial artery wall 3 hours and 30 days after catheterization with a 6 F sheath for diagnostic or interventional coronary procedures and elucidate arterial healing patterns that might explain early radial artery…
This quantitative research project was preceded by a qualitative study (Sexuality in people with a limb amputation and their partner: a qualitative study; METc 2010/179). The aims of the current study are to explore:- which sexual problems occur in…
To evaluate the long-term clinical effectiveness of patients with IC randomized for supervised exercise training orendovascular revascularization.
In the past there has been little attention for quality of life, of which sexuality is an important part, in both scientific research and in clinical practice. Nowadays things are changing and talking and thinking about the sexual functioning and…
The objectives are to explore in a step-wise approach the possibility to study reactive hyperemia and ischemia-reperfusion phenomena in humans by simultaneous assessment of vaso-reactivity and autonomous nervous system function.
Determine if there is a difference in permeability of the blood brain barrier between the twodifferent types of cerebral small vessel disease.
The aim of this study is to explore the elementary components in shared goal-setting in patients with no-option CLI. The transcending benefits of this study will apply to doctor-patient communication in general. The primary objective of the study is…
to investigate the safety and efficacy of idarucizumab in reversing the anticoagulation effect of dabigatran, in patients who have uncontrolled bleeding or require emergency surgery or invasive procedures.
In men without erectile problems, night time erections occur during the REM-sleep. For this study we will compare the current diagnostic test, the Rigiscan, with the data from de TRIP-Patch during the night. To validate discriminating sensor-…
To investigate the impact of different doses of handgrip exercises (moderate vs high intensity) and stimuli (exercise vs ischemia) on the ability to protect endothelial damage from ischemia-reperfusion injury in healthy humans. A secondary goal is…
Determine the difference in mitoPO2 in between the cannulated and non-cannulated and the difference in DLS red blood cell velocity (RBV) between the two legs, in patients undergoing a cardiopulmonary bypass (CPB) MICS with standard cannulation.
To establish the relationship between past illness with SARS-CoV2 infection and endothelial dysfunction.To study the long-term effects of SARS-CoV2 on endothelial function.To explore the influence of Covid disease severity on the degree and duration…
To explore the impact of different types (high-intensity vs moderate-intensity cycling), modes (whole bodycycling vs local handgrip) and stimuli (exercise vs ischaemic) of preconditioning on the ability to protect endothelial damage in response to…
To measure saturation and desaturation of the cavernosal tissue with a cutaneousplaced penile sensor, before and during full rigidity. To validate discriminatingsensor-readings between flaccid state and full rigidity of the penis. To explore the…
To explore whether vigorous endurance exercise (i.e., running a marathon) alters the magnitude of cardiac damage following myocardial ischemia-reperfusion injury in amateur athletes through using an ex vivo rat heart model of myocardial infarction.
This study will assess the patient* health status regarding vascular symptoms after TF-AVI procedure together with stent function and the rate of stent fractures
The present study will investigate the association between Blood-Brain Barrier leakage and cognitive aging.Primary research question:1. a. Is stronger BBB leakage associated with greater decline in episodic memory?b. Post-hoc explorative analyses…