286 results
To test the use of RFA and ER in a single endoscopic session in 20 consecutive patients with a BE containing visible abnormalities with HGD or EC upon biopsy.
1. To determine the feasibility of SLNM in CRC.2. To assess the accuracy of SLNM in the status of the regional nodes.3. To identify aberrant mesenteric lymphatic drainage patterns.
To recognize the distribution pattern of 111In-bevacizumab in patients who show response on treatment with bevacizumab. The ultimate goal is to identify and select patients who can be successfully treated.
It seems logical that when the same treatment is applied before surgery, that patients will tolerate this easier. Analogous to rectal cancer it is assumed that by reducing tumor size, surgical outcome can be improved. In this preoperative approach,…
Hypothesis.In women with preeclampsia endovascular remodeling and invasion of the spiral arteries is less prominent which will result in overwhelming placental oxidative stress and pregnancy failure. Abnormal function of trophoblast and stroma cells…
The objective for this study is to investigate different types of techniques and strategies, in order to optimize scan-parameters, image quality and patient acceptance in Magnetic Resonance Colonography.
1. to compare the detection rate of colorectal polyps and cancer by CCE versus conventional colonoscopy in a surveillance population. 2. to investigate patients* acceptance, perceived burden and preference for surveillance test.
To validate the production of large-scale, total tumor RNA loaded, matured and functional DCs from periferal blood monocytes from patients with EAC and PC.
Aims of this study are:1) To study the endoscopic and histological regeneration pattern of NSE after RFA of BE.2) To compare the histological and immunohistochemical characteristics of NSE to normal untreated squamous epithelium.3) To compare NSE,…
To quantify rectal tumour motion using (cine-)MRI and to correlate this motion with rectal wall movement in order to check the feasibility for CBCT controlled dose escalation for rectal cancer.
1. Organization and controlled implementation of ColoPrint® for prognosis prediction2. In stage II patients, prospective comparison of risk assessment by ColoPrint profile versus clinical parameters based on local protocol and ASCO high-risk…
The purpose of this project is to determine and analyze miRNA expression profiles from freshly frozen human colon tissue as well colorectal adenomas and carcinomas to identify specific miRNAs or miRNA clusters whose expression is altered in…
Primary objectiveThe primary aim of the study is to determine the prevalence and incidence of small bowel neoplasia in Lynch syndrome patients using small bowel CE and DBE.Secondary objectivesThe secondary aim is to identify risk factors for small…
To validate FDG-PET segmentation tools for radiation target volume definition by correlation of CT and FDG-PET volume measurements with histology of nodal metastases of squamous cell carcinoma of the head and neck.
To determine if there is an increase of skin-autofluorescense in subjects undergoing elective colorectal surgery.
(1) To evaluate the feasibility and accuracy of confocal endomicroscopy during colonoscopic surveillance; (2) To compare the accuracy of CE / NBI / AFI with the accuracy of confocal endomicroscopy for the endoscopic differentiation of adenomatous…
1) To identify a tumour genetic profile that is associated with early metastatic spread in patients presenting with oesophageal cancer and no evidence of distant metastasis at the time of diagnosis.2) To distinguish oesophageal cancer patients who…
The aims of this study are: 1) To prospectively determine the incidence of HPS/polyps and CRC in first-degree relatives of patients with HPS so as to define whether screening of this group is justified.2) To assess the proportion of individuals that…
1) to sample ACF in colorectal mucosa of patients without an increased risk of CRC, patients at an increased of recurrent advanced adenoma based on a personal history of adenomas, patients with established CRC and patients with HNPCC and to…
The aims of this study are: 1) to evaluate the neoplasia miss-rate of AFI in patients with longstanding UC during colonoscopic surveillance; 2) to evaluate the feasibility of miniprobe-based confocal endomicroscopy in these patients; 3) to compare…