19 results
The objective of the study is to map in a standardized way the phenotype of carriers with known LHON mutations. We want to study the natural course of persons with LHON mutations by examining patients several times. Further, we want to study a…
1. To determine if zinc supplementation in AMD patients has a direct measurable effect on the complement system explaining the mechanism through which this substance exerts its influence on AMD progression.2. To determine whether this proposed…
This study has the following goals: 1. Generation of normative values for full-field ERGs within single recording sessions according to ISCEV standard.2. To compare function (results of full-field ERG) with anatomy (retinal thickness on OCT) in…
The aim of this study is to investigate whether skin autofluorescence (AF) is predictive of postoperative PVR (and corresponding surgical failure) in patients being surgically treated for retinal detachment and to investigate some pathways which may…
Assess correlation between CFH polymorphism and the effect of laser treatment of drusen.
the study aims to answer the following question:are components of innate immunity in general, and the complementsystem in particular, correlated with and usefull as predictors for the occurrence of macro- and/or microvascular complications in a high…
To determine the natural history and long term (10 years) outcome of CSR.
What is the contribution of the different variations in the C1-inhibitor gene to the disease AMD?
Quantification of the incidence of postoperative CME in DSAEK patients.
To collect data in order to create a registry that can be used for research in PXE, partly with an international questionnaire, and to measure PPi, ENPP1 activity, anti-retinal antibodies and cytokines, and retinal calcification in all patients…
To determine whether functional and/or structural retinal biomarkers or circulating biomarkers are able to differentiate people with mild cognitive impairment (MCI) within the type 2 diabetes (T2D) population (this we will be able to do in the…
Objective: To collect a broad array of clinical, behavioural, physical and biochemical parameters, to ensure that many clinical research questions or problems related to successful aging with T1D can be answered. Nevertheless, we have a priori…
The aim of this study is to get more insight in the pathogenesis of (P)SCR by comparing: (1) Red cell characteristics (deformability and point of sickling in hypoxia measured by the Oxygenscan), (2) Angiogenesis by determining several biomarkers of…
To correlate structural modifications with visual function in patients after macula-on retinal detachment.
To study the progression of high and pathologic myopia over time.
The primary objective of this study is to investigate the association between smartphone use and risk of myopia in teenagers.
1. To further unravel biochemical abnormalities in SLS patients2. To study neuro-retinal changes over time to learn more about involved neurons and pathomechanism of ophthalmologic abnormalities in SLS patients 3. To study quality of life and daily…
The objective of this pilot study is to measure the ODR of the retinal vessels in infants at risk of developing ROP. The secondary objective is to measure the vessel diameter of the retinal vessels in infants at risk of developing ROP
To demonstrate choroidal thickness of emmetropic and myopic CSC patients to be significantly different.