76 results
The objective is to assess the gait characteristics of adults with intellectual disabilities by other causes than Down syndrome, and without diagnosed neurological conditions (Parkinson's disease, cerebrovascular accident, dementia, and…
The aim of this study is to test the feasibility, reliability and validity of a Dutch version of the Penn Computerized NeuroPsychological testing system (CNP). It is tested wether our translated version is feasible for use in the Dutch population at…
The primary objective of this study is to provide access to SPD503 following participation in SPD503-315 or SPD503-316. The primary outcome of this study is to evaluate the long-term safety of SPD503. The evaluation of safety will be based on the…
This pilot study is set up to test the feasibility of the BrainGame Brian program in a small subsample of very preterm children at 8 to 10 years of age. Evidence that the program is feasible and differences in EF between pre-training assessments and…
The objective is to examine the physical fitness of children with moderate to severe intellectual disability.
Primary objectives:This is a pilot study. The main objective is to investigate the feasibility of the study. This feasibility will be tested by estimating: 1. the percentage of inclusion, 2. the incidence of behavioural changes for which the GP is…
The aim of this project is to gain insight in which somatic, cognitive and psychosocialfactors contribute to preservation of functioning, in order to identify older people with potentialrisk of functional decline in an early stage and develop…
The main purpose of the proposed naturalistic pilot study is to compare postsynaptic DA receptor binding (reflecting synaptic DA concentrations) and brain Phe levels in PKU adults with lower blood Phe levels with PKU adults with higher blood Phe…
Primary: The primary objective of this study is to evaluate the long-term safety of SPD489 administered as adaily morning dose (30, 50, and 70mg) in the treatment of children and adolescents (6-17 years of ageinclusive at the time of consent in this…
The goal of the study is to estimate the prevalence of patients with ADHD in adult outpatient care. About 2300 patients in 8 European countries will participate to this trial. This data will improve the knowledge about the presence and the…
To establish the pharmacokinetic profiles of saliva and plasma concentration of 10 mg MPH-IR and 18 mg MPH-OROS in healthy volunteers; to investigate whether there is a correlation between saliva- and plasma levels of MPH-IR and MPH-OROS, and if…
The overall objectives of CLEAR are to improve our global understanding of the longitudinal impact ofattention-deficit/hyperactivity disorder (ADHD) and contribute to the body of scientific evidence regarding thetreatment and evolution of ADHD over…
To evaluate whether cognitive function of formerly preeclamptics is diminished and correlated with dynamic cerebrovascular control properties using non-invasive measuring techniques (dynamic cerebral autoregulation, neurovascular coupling). Question…
The goals of this study is twofold:At first we want to gain insight in neurocognitive functioning of children and adolescents (12-18 year) with JSLE.Secondly, we want to adapt and validate a Dutch translation of a short "Quality Life…
The aim of the study is to investigate the effects of atomoxetine on driving performance compared to placebo in 30 adult patients with ADHD. An auditory oddball paradigm will be presented and EEG will be measured during driving to gain insight in…
Primary objective:To determine the most important risk factors for falls in elderly people with mental retardation and to describe which of these factors may be modified by intervention/treatment, in order to prevent falls.Secondary objective:To…
In the present study we propose two TMS experiments, in which we want to examine the brain areas crucially involved in the processing of emotional prosody in healthy right handed subjects.
The main objective of the study is to develop a valid and efficient screening procedure to identify frail older subjects who find themselves in a complex care situation. The study basically addresses three research questions, concerning:1) The…
primary:To assess absolute bioavailability of S 47445 after administration of a single oral potential therapeutic dose and to determine the blood and urinary pharmacokinetic parameters of S 47445 after administration of a single i.v. microdose of […
The research question targets the validation and examination of norm scores of the ToM test-R test in the mental disorders PDD, ADHD, and social phobia in children of different ages. It will be investigated:(1) Whether or not differences in *theory…