71 results
The objective of this study is to evaluate whether an in- or outpatient initiation of the brace treatment has an influences short and long term brace compliance.
The objective of the study is to investigate vertebral bone marrow fat fraction and bone mineral density during surgery induced weight loss.
The objective of the study is to obtain information on the bioavailability and pharmacokinetics of the phenolics present in an olive leaf extract (Bonolive®, dose 250 mg), standardized on 40% oleuropein, and to identify the composition of the…
The aim of this prospective cohort study is threefold: (1) for a better understanding of MTSS' underlying pathophysiology, (2) to assess the QU's reliability in healthy subjects and subjects with MTSS and (3) to assess the validity of QU…
To investigate the long term stability (> 5 yrs) in patients treated with mandibular distraction osteogenesis (MDO) for correction of a Class II-occlusion. Hypotheses:1) MDO is a technique for mandibular lengthening with comparable stability…
Part 1: Quantification of individual patient-prosthesis interactions- Determination of the instantaneous effect of prosthetic knees with variable biomechanical properties on the gait pattern of PULAs (Part Ia). - Determination of the influence of…
• Compare bone density between patients with mild haemophilic and those with severe haemophilia*.• Compare the relationship between treatment regimen: prophylactic (high-dose vs. intermediate dose) and on-demand and bone density.• Examine the…
Primary Objective: - Are there mesurable changes in biochemical markers after BSSO in serum(CTX, P1NP, BALP, Osteocalcine, Calcium, vit D. CRP, BSE, leucocyten, IL6, creatine) and in urine(hydroxylysylpyridinoline en lysyspyridinoline)? - Can serum…
To increase to knowledge of how adults with OBPL function, this research will be done with de next researchquestion: what iare the lengterm consequences of OBPL among adults? These questions are being adressed to with fhe ICF structure:- body…
To investigate in vivo whether a measurable increase in systemic ATP levels occurs in response to mechanical stimulation of bone in humans.
Is the lateral chest X-ray useful to look for vertebral fractures using the semiquantative method of genant in the geriatric population? Our hypothesis is that the lateral chest X-ray is a good alternative, with high sensitivity and specificity…
It is our goal to predict the efficacy of glucocorticoid-treatment of RA patients by means of a list of markers predicting the reponse to GC treatment in order to avoid ineffective but potentially harmful treatment in the glucocorticoid non-…
This pilot study will evaluate whether tumour hypoxia can be demonstrated in the bone marrow compartment of relapsing MM patients by using the tracer 18F-FAZA. The results will be compared with the results of the FDG-PET scan. In addition in vitro…
To investigate the differences in facial analysis, between patients with acromegaly, being in remission, and healthy subjects, and to investigate the changes in relational proportions between these facial structures.
To determine the incidence of vertebral fractures and exploring riscfactors in the geriatric outpatients.The effect of new vertebral fractures on daily activities, quality of life, reported falls.To explore the relation between frailty syndrome…
The aim of this study is to evaluate the influence of extreme fixed wrist flexion and ulnar deviation due to spasticity on bone shapes of the wrist bones. We want to compare CT scan-based three-dimensional reconstructions of the spastic wrist to the…
The purpose of the study is to investigate whether the cyclodextrin added to the cholecalciferol formulation has an effect on the vitamin D3 availability in the body. Thus, it will be investigated if concentrations of vitamin D3 that are found in…
The primary objective of the study is to evaluate the effect of denosumab 60mg every 6 months (Q6M) compared with Actonel 150mg monthly (QM) on total hip Bone Mineral Density (BMD) at 12 months in postmenopausal women transitioning from previous…
1.To investigate if [18F]Fluoride PET-CT is a potential imaging technique for assessment of (changes in) disease activity of ankylosing spondylitis on baseline and after anti-TNF therapy (with MRI and clinical outcome as reference).Sub-study in 2…
May DXR replace DXA as a screeningstool for osteoporosis