78 results
to determine the percentage of patients with CKD, without a history of gout or attacks of arthritis, that have tophi measured by US,DECT and clinical examination. to determine the percentage of patients with CKD, that have tophi measured by US, and…
Primary aim: Stepwise feasibility study to investigate whether intravenously administered macrophage tracers [11C]DPA-713, [18F]DPA-714 and/or [18F]PEG-folate accumulate in inflamed joints of rheumatoid arthritis patients using PET(-CT).Secondary…
The main objective is to identify objective, neuromuscular and/or mechanic parameters through movement analysis, which are closely correlated to the subjective outcome of TKA. Secondary objective is to generate parameter specific hypotheses for our…
The main objective of this study is to assess the prevalence cardiovascular disease and the prevalence of risk factors for cardiovascular disease in patients with gout, and to quantify the risk for cardiovascular disease in patients with gout. The…
The aim of this exploratory study is to compare the hemodynamic response as determined by the HandScan between patients with OA and RA, and to study these hemodynamic responses in relation to disease specific underlying joint pathology (synovial…
To evaluate the role of white blood cell (WBC) scintigraphy in monitoring the response of infection treatment of a prosthetic joint infection.
Arthroscopic Optical Coherence Tomography in imaging of Trapeziometacarpal joint articular cartilage
In-vivo visualization of TMC articular cartilage using intra-articular fiber-optic OCT during TMC arthroscopy.
To estimate the prevalence and burden of disease of PsA among PsO patients in primary care,.To test the ability of the PEST(1), the PASE(2) and the EARP(3) to detect cases with PsA in primary care.To develop an easy applicable prediction rule for…
Primary objective:Pharmacokinetics/-dynamics of 124I-F8IL10 Secondary objective:Dosimetric parameters of arthritic joints and internal organs.
In the present study we evaluate the change in quality of cartilage and bone as a result of KJD and of HTO. Based on the results of this pilot study, we will design a clinical study, with sufficient power, using the most promising sequences to…
The primary objective is:* to assess the accuracy of DCE-MRI in detecting joint inflammation as compared to physical examination in the evaluation of different stages of disease activity in JIA patients The secondary objectives are:* to evaluate the…
Answer the following questions:1. What are the long term results (>20y) of patients with a primary total knee prosthesis (type Total Condylar) for different endpoints:a. Removal of the prosthesis. (with or without re-implantation)b.…
The primary objective in this study is to evaluate effectiveness of optimized high cervical epidural neurostimulation against placebo-stimulation in patients with intractable cervicogenic headache in a neurostimulation trial.
The aim of this study is to determine the sensitivity of ultrasound in diagnosing the presence of an OCD in the ankle joint at locations that can be visualized compared to CT.
With this study we want to get more insight in genetic characteristics that are able to predict the susceptibility to joint damage in haemophilia patients. Therefore we want to determine the association between the (GT)n-repeat length within the…
To conduct a pivotal study to determine the independent predictive validity of several soluble biomarkers (e.g. MMP3, CTX-II, CTX-1, OPG, RANKL) considered to be high priority candidates for predicting structural damage in RA according to the…
This study investigates the use of MRI during diagnostic workup for children presenting with hip pain and compares the usefulness of MRI to conventional radiography and ultrasound.
Primary aim: To investigate whether PET-CT (using [18F]FDG, [18F]Fluoride and [11C]PK11195 as tracers) visualizes inflamed tissues of AS patients, with clinical scores as reference Secondary aim: To investigate whether reduction of inflammation by…
Primary ObjectiveTo define normal values for synovial thickness in the healthy pediatric knee and wrist on MRI after intravenous gadolinium contrast administration. Secondary ObjectiveTo evaluate possible age-dependent variations in normal values…
We hypothesize that all different novel quantitative radiological imaging techniques under investigation in this project are a measure for cartilage quality in terms of the sGAG content, collagen content, or a combination of both.The primary…