77 results
Most patients undergoing spine surgery with pedicle screw instrumentation will experience insufficient pain relief in the first three days after surgery, whereafter postoperative pain can be managed with conventional, non-opioid analgesics in most…
Objective The objective of this study is to assess which risk scoring model is most cost-effective for the discrimination between benign and malignant ovarian tumors that guides referral decisions for women with ovarian tumors in the Netherlands…
Measuring tFUS-dependent changes in behaviour (in our target tasks) when targeting deep brain regions [Behavioral Objective]
To explore, whether markers of mitochondrial dysfunction measured in isolated PBMCs or immune cell subpopulations differ between subjects with mitochondrial disorders and cardiomyopathy and healthy volunteers.
Primary Objective: Does DBS result in cognitive changes in patients with OCD on the long term? Secondary Objective(s): Does DBS result in personality changes in patients with OCD on the long term?Are certain cognitive profiles associated with…
To investigate the effect of whey and casein ratio of IFT on intragastric behavior, gastric emptying and postprandial plasma metabolome
To assess whether co-ingesting keto-analogues of branched-chain AAs along with protein during HD can attenuate HD-initiated muscle catabolism.
The aim of this study is to investigate the concept of fear of progression among advanced incurable cancer patients onongoing systemic treatment.
Primary Objective: To quantify the variation in post-prandial plasma AA profiles between (and within) individuals after consumption of a poorly digestible plant protein source (lucerne). Secondary Objective: To compare the variation in postprandial…
To assess the impact of protein in a solid (bar) and liquid (drink) form on post-prandial amino acid responses in vivo in healthy young women.
The primary goal is to compare functional (language) areas in the brain found by preoperative fMRI, to those found during intraoperative ESM (electrical stimulation mapping) and fUS (functional ultrasound) during awake craniotomies, to see whether…
To assess the spatial topographical representation of anger and behavioural inhibition in the cerebellum.
To study the effect of individual control of the light on thermal comfort
The objective of this proof-of-concept study is to investigate (differences in) small intestine microbiota and postprandial glycemic responses.
Obtain phased-contrast 4D flow MRI scans in 20 healthy volunteers to quantify local blood flow in the thoracic and abdominal aorta and extract boundary conditions for future in vitro studies. Furthermore, the 3D geometry of the vessels within…
The purpose of this study is to evaluate the user experience of InPen* with InPen Diabetes Management App and Guardian * 4 system in adult patients with type 1 diabetes for the design of a future pivotal study.
Primary outcome is to assess HRQoL in high risk and advanced melanoma patients treated with immune checkpoint-inhibitors. Secondary outcomes are to describe anxiety and depression; fear of cancer recurrence; melanoma-specific HRQoL; symptoms and…
The objective of the proposed study is to determine whether the neural mechanisms of word learning change with age. In line with this, we aim to investigate whether the activity of brain regions in this L2 word learning process relate to neural…
to test the feasibility of the study protocol for operability, intensity and logistics and to test whether the chosen activities can be measured as expected, in order to provide a guideline for testing maximum aerobic capacity and the metabolic…
We here validate the algorithms for movement analysis that were developed previously in healthy participants (METc 2019.542; regarding quantitative aspects of movement) and that were derived from a review of the literature (regarding qualitative…