68 results
The present study will examine how young-onset-dementia patients and their families can be supported in their home environment as long as possible and institutionalisation can be delayed. For this the functioning and care needs of young-onset-…
The present protocol addresses these issues, with a systematic approach where we first assess optimal settings for BCI, and then test the quality of BCI application in adequately sized groups of subjects. The whole project is aimed at obtaining a…
the objective of the current study is to evaluate the safety and efficacy of enzyme therapy in the Dutch population of patients with MPS I, II and VI; to compare this to the natural course of these diseases; to make an inventory of the direct and…
The main objective of this specific study is to examine to what extend differences in cognitive functioning between people are due to complex interactions between genes and environment.
I. Evaluation of the nature and maintenance of specific cellular immune mechanisms after infection with Bordetella pertussis in different age groups, to identify critical parameters for pertussis re-emergenceII. To relate individual patient*s…
Using pedigree research in two CVID-families to find clues for genetic testing.
The aim is to study if Neurofeedback can be an applicable intervention.for survivors of childhood brain tumours. The QEEG wil be investigated whether under or overactive brainareas exist which can be trained. This study will also investigate whether…
To assess normal values of echocardiographic parameters and exercise tolerance as asssessed by bicycle ergometry in healty schoolchildren 12-18 years old.
To gain insight in the risk of transmission of tick-borne micro-organisms Borrelia, Ehrlichia, Rickettsia and Babesia to humans and to gain insight in risk factors.
The primary objective is to determine the pharmacokinetic characteristics of galantamine after 2 single oral doses in children with Down syndrome. Secondary objectives are to evaluate safety and tolerability.
To identify novel childhood cancer-predisposing genes in children.
To investigate the onset and short term natural course of ADD and TMJ hypermobility in children, and to give insight into some related risk factors.
The objective of the study is to determine what the clinical value is of measuring GE of liquids in 50 SMID children. The primary study parameter is how often DGE of liquids occurs in this study group. Secondary study parameters include…
The main objectives of this study are to describe behavioural problems in children aged 0 to 4 years and posttraumatic stress symptoms in children aged 8 to 17 years and to study the course and determinants of these problems. Further, this study…
The aim of this project is to collect new normative data for the Dutch children, for both parts of the M-ABC2. The opportunity will also be taken to extend the age range of the test down to 3 years and up to 16 years. Also the reliability and the…
In patients who have undergone surgical repair of TOF, we aim to- assess the development of RV dimensions and function in relation to clinical outcome, in a time dependent manner,- identify, chracterize and quantify markers in blood samples, using…
The purpose of this study is to improve, implement and evaluate an intervention program to improve physical activity in daily life and sportsparticipation of adolescents and young adults with MMC. The purpose of the intervention "Active…
The purpose of this investigation is identify thecausative oncogenes in 17p11.2-p12, to clarify the mechanism of their amplification, and to determine their diagnostic and prognostic importance for patients with osteosarcoma.
To determine the feasibility of a trainingprogram in childhood cancer survivors in the primary health care system